Thirteen (13) patients with liver neuroendocrine carcinomas metastases, positive for somatostatin receptors, confirmed by scintigraphy were infused with 4070-7030 MBq per session of In-111-octreotide after selective hepatic catheterization, exploiting the catastrophic activity of Indium Auger and Internal Conversion electron emission on cell DNA. Evaluation of the treatment was assessed by ultrasonography (US) as well as by computed tomography and/or magnetic resonance imaging scans. US appears to be the imaging procedure of choice because the examination is sensitive for evaluating lesions' edema and cystic components, provides precise measurement of tumor size, and is inexpensive. Degeneration US signs were classified in stage I (an echolucent rim in the periphery of the lesion), stage IIa (lesion with large cystic spaces), stage IIb (tiny cystic spaces) and stage III (absorption of the cystic component or stable cystic remnants).
A survey was conducted in the Athens region between the years 1996-1997, in which 33 CT scanner facilities from the 67 operating in this area participated. Examination frequencies from the 33 scanners were 187,875 per year for all types of examinations. Using published estimations for the mean effective dose for each type of examination, it was estimated that the collective dose from the above examinations was about 1,100 person-Sv, which, if projected to the total number of 152 CT scanners operating in Greece at the time of the survey, results in about 0.5 mSv per caput dose each year for the Greek population, which is probably the highest in Europe.
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