Intravitreal ranibizumab is highly effective in improving or stabilizing vision and lesion morphology in patients with macular choroidal neovascularization secondary to angioid streaks.

Purpose To assess the effect of hyaluronidase on eye and eyelid movements when used as an adjunct in sub-Tenon's anaesthesia. Methods A total of 60 patients who had subTenon's anaesthesia prior to phacoemulsification surgery were divided into two equal groups in a double-masked randomised controlled fashion. Of these, Group A had 4 ml lignocaine 2%, while Group B had 4 ml lignocaine 2% with the addition of sodium hyaluronidase 75 IU/ml. Ocular motility, levator, and orbicularis oculi function were measured in all patients at 5 and 8 min. Levator function was scored from 0 (no function) to 3 (complete function) while orbicularis function was scored from 0 to 2. The score for ocular motility was the sum in four positions of gaze, each position scoring from 0 to 2. Results were compared using a nonparametric test. Results Group B achieved significantly better ocular and lid akinesia than Group A both at 5 and 8 min with Po0.01. The median scores for levator function at 5 and 8 min were 2 for Group A and 0 for Group B. For orbicularis function, the median scores at both time intervals were 2 for Group A and 1 for Group B. For ocular motility, the median score for Group A at 5 min was 3 and at 8 min was 2.5; for Group B at 5 min was 0.5 and at 8 min was 0. Conclusions The addition of hyaluronidase in sub-Tenon's anaesthesia has a significant effect in improving ocular and lid (levator and orbicularis) akinesia.

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Background: Despite a signifi cant body of research, no consistency on postoperative foveal thickness as measured by optical coherence tomography (OCT), can be recorded. The purpose of our study was to evaluate the effect of uncomplicated cataract surgery in the thickness of the retina in the foveal area during the early postoperative period. Methods: In a prospective study, 79 eyes were assessed by OCT, on day 1, and weeks 2 and 4 after uncomplicated phacoemulsifi cation with intraocular lens implantation in the Athens University Clinic. The outcome measure was the thickness of the retina in the foveal area. Results: The thickness of the retina preoperatively is signifi cantly smaller (150.4 ± 18.8) (p Ͻ 0.05) than the thickness of the retina on day 1 (171.8 ± 21) and week 2 (159.7 ± 19) and returned to the initial levels on week 4 (152 ± 17.1). The estimated correlation coeffi cients between preoperative and postoperative thickness of the retina were signifi cant (p Ͻ 0.05). Conversely, no association was found between postoperative visual acuity and thickness of the retina, neither between the phacoemulsifi cation energy and retinal thickness. Operation time, although inversely related with postoperative visual acuity, was not associated with the thickness of the retina. Conclusions: Following phacoemulsifi cation, an increase in the foveal thickness was detected in the early postoperative period, quantifi ed and followed up by OCT. The foveal thickness returned to the preoperative level, 1 month following surgery in our study. No association was shown between intraoperative parameters and increased postoperative retinal thickness.

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