Sebaceous carcinoma is a very aggressive malignant tumor, derived from the adnexal epithelium of sebaceous glands. Extraocular sebaceous carcinoma is a very uncommon neoplasm usually localized on the head and neck. To our knowledge, there are only 2 previously reported cases of sebaceous carcinoma on the penis. We report the clinicopathologic data on 3 additional cases of sebaceous carcinoma arising in the penis. Treatment is debatable in view of the fact that this kind of tumor has a high recurrence rate and early regional lymph node involvement. Considering these facts, we used preoperative lymphoscintigraphy, intraoperative lymph node mapping and sentinel node biopsy before performing a bilateral inguinal lymphadenectomy in 1 of 3 patients treated in our institute.
Sebaceous carcinoma is a rare and aggressive skin tumor. It can be located in any
area of the body, the most commonly involved area being the periorbital region. It
does not entail a typical clinical presentation, which explains the often late
diagnosis. The aim of this report is to outline the rarity of the disease and its
atypical clinical description, since to this day, inguinal ulcers with clinical
manifestation have not been reported. We present and discuss a case of sebaceous
carcinoma with an unusual clinical presentation, in an elderly male patient. The
precise approach to genital ulcers, as shown in this case, is a diagnostic challenge
that requires a great deal of effort on the part of the clinician.
Tumor carcinoide gástrico: reporte de un caso en el Servicio de Oncología Clínica del Instituto de Previsión Social (IPS)
RESUMENIntroducción: Los tumores neuroendocrinos (NET) son tumores compuestos por un grupo heterogéneo de neoplasias, diagnosticados con baja incidencia en nuestro medio. La gran mayoría corresponde a origen gastrointestinal, seguido por la localización pulmonar. Dentro de los tumores neuroendocrinos se hallan los tumores carcinoides; cuya presentación a nivel gástrico es de un 2 %. Presentación del caso: Se presenta un caso de tumor c a r c i n o i d e g á s t r i c o c o n s í n t o m a s t í p i c o s diagnosticado y tratado en el HC-IPS; la tomografía, la endoscopia digestiva alta con toma de biopsia determinó la localización, morfología y la histología de esta enfermedad. Se confirmó con la positividad de cromogranina A y sinaptofisina en el estudio inmunohistoquímico. El tratamiento incluyó la resección del tumor y administración de octreotide desde hace 8 meses, con buena evolución, en seguimiento por equipo multidisciplinario complejo.Conclusión: Los tumores neuroendocrinos constituyen una entidad oncológica de difícil diagnóstico por la complejidad de los signos y síntomas que se enmascaran tras los tumores epiteliales gástricos, siendo la inmunohistoquímica el pilar principal para el diagnóstico.
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