MRSA colonization among HIV-infected youth is more closely related to living in a low-income or slum community than to HIV-related clinical factors. High genetic MRSA isolate diversity in our population suggests frequent transmission.

ResumoObjetivo: avaliar as formas de apresentação clínica da enterocolite necrosante neonatal e os fatores associados à doença.Métodos: estudo retrospectivo dos casos de enterocolite necrosante neonatal (ECN) (n=56) ocorridos na UTI Neonatal Lagoa, entre dezembro de 1986 e julho de 1992. O diagnóstico e o estadiamento da doença seguiram o critério de Bell modificado. Foram avaliados o diagnóstico e a evolução de todos os casos. Posteriormente, foram selecionados os casos de enterocolite grau II e III (n=44) e comparados com um grupo controle (n=44), selecionado pelo peso de nascimento (± 250g) e época de internação (± 2 semanas). Para a análise estatística, foi considerado significante p<0,05.Resultados: dos 2.447 recém-natos internados na UTI, 56 (2,3%) evoluíram com enterocolite. O peso médio dos pacientes foi de 1.908,5g; a idade gestacional média, de 35 semanas e um dia; a idade média do diagnóstico foi de 10,7 dias; 51 (91,1%) pacientes foram alimentados anteriormente ao diagnóstico; 18 (32,1%) necessitaram de cirurgia de urgência; em 9 (16,9%) as hemoculturas foram positivas; 10 (17,8%) pacientes faleceram. Observaram-se quatro padrões evolutivos da doença: aguda fulminante, aguda com pneumatose, insidiosa e suspeita. Comparativamente ao grupo controle, três fatores associaram-se significativamente à enterocolite: apnéia (p=0,045), a progressão rápida da dieta (acima de 20 ml/kg/dia) (p=0,048) e a presença de agente infeccioso (p=0,000).Conclusões: os fatores associados significativamente à enterocolite foram a ocorrência de apnéia, a progressão rápida da dieta e a identificação do agente infeccioso. AbstractObjective: to evaluate the features of clinical presentation of neonatal necrotizing enterocolitis and its associated factors.Methods: retrospective study of the cases of neonatal necrotizing enterocolitis (n=56) diagnosed at Neonatal Intensive Care Unit Lagoa (NICU), between December 1986 and July 1992. Diagnosis and stages of the disease followed the modified Bell's criteria. Diagnosis and follow-up of all cases were evaluated. The cases of enterocolitis -degrees II and III (n=44) -were subsequently selected and compared to a case-control group (n=44), selected according to birthweight (± 250 g) and hospitalization period (± 2 weeks). The statistically significant analysis was considered as p < 0.05.Results: out of 2,447 newborns admitted to the NICU, 56 (2.3%) presented enterocolitis. Mean weight was 1908.5 g; mean gestational age was 35 weeks and 1 day; mean period for diagnosis was 10.7 days; 51 (91.1%) patients were fed before diagnosis; 18 (32.1%) needed urgent surgery; nine (16.9%) hemocultures were positive; 10 (17.8%) patients died. Four clinical standards were observed: fulminant, acute with pneumatosis, insidious and suspect. Comparatively to the case-control group, three factors were significantly associated with enterocolitis: apnea (p=0.045), rapid increase of food intake (< 20 ml/kg/day) -(p=0.048) and presence of infectious agent (p=0.000).Conclusions: significant factors associated w...

No abstract

Clinical improvement with regard to texture, firmness, wrinkle depth, skin coloration, and clearance of actinic keratoses was observed. Histopathologic and morphometric studies were consistent with the clinical findings.