Purpose To compare selective laser trabeculoplasty (SLT) with conventional argon laser trabeculoplasty (ALT) in terms of hypotensive efficacy, anterior chamber inflammation, and pain reported by the patients treated. Methods A prospective study performed on 40 consecutive patients. Group I (n ¼ 20): SLT 1801. Group II (n ¼ 20): ALT 1801. Intraocular pressure, flare (Laser-Flare-Meter, Kowa FM-500, Japan), and pain (Visual Analogue Scale) were measured before treatment and 1 h, 24 h, 1 week, and 1, 3 and 6 months after treatment. Statistically significant differences were determined by an independent-sample Student's t-test. Results At 6 months after treatment, pressure reduction was similar in both groups: SLT 22.2% (range 0-36.3%) and ALT 19.5% (range 0-30.2%), P ¼ 0.741. The energy released during treatment was significantly lower in SLT (48.3 SD 7.4 mJ) than in ALT (4321 SD 241.7 mJ), Po0.001. At 1 h after treatment, anterior chamber flare was also lower in SLT (13.3 SD 6.3 vs 20.7 SD 7.4 photons/ms), P ¼ 0.003. Pain reported by the patients during the treatment was significantly lower in SLT (2.0 SD 0.7 vs 4.3 SD 1.3), Po0.001. Conclusions The hypotensive efficacy of both lasers at the end of follow-up was similar. The energy released during treatment and inflammation produced in the anterior chamber in the immediate postoperative period were significantly lower for SLT. The SLT procedure was better tolerated, producing less discomfort during treatment than conventional trabeculoplasty with argon.

Purpose To evaluate the long-term efficacy and safety of infliximab as treatment for noninfectious posterior uveitis. Methods An open-label clinical trial including seven patients (12 eyes) with posterior uveitis refractory to conventional treatment regimens with corticosteroids and at least one immunosuppressive agent. Three intravenous doses of 5 mg/kg of infliximab were administered at weeks 0, 2, and 6. Infliximab infusion was repeated in patients undergoing a relapse of uveitis after initial remission. Improvement was defined as amelioration of visual acuity or disappearance of retinal exudates and/or haemorrhages, decreased macular oedema and/or vitreous opacities. All patients were followed up for at least 36 months.

Confocal microscopy is a useful tool for the diagnosis of corneal argyrosis because it allows the in vivo visualization of silver deposits at different corneal levels.

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The reported shift of fixation to a more central position when a red filter is placed before an eye which fixates eccentrically, has never been satisfactorily explained. To further investigate this phenomenon, 14 subjects with eccentric fixation were recruited. A Wratten No. 92 filter was placed before the eccentrically fixating eye, and any change of fixation was assessed by the after-image transfer test. A neutral density (ND) filter was then used, to mimic the reduced retinal illumination caused by the red filter. The results suggest that there is a significant reduction in the eccentricity of fixation, when placing the red filter before an eccentrically fixating eye, and also when placing the ND filter. No significant difference in the effects produced by either filter was found. This suggests that it is the reduction in retinal illuminance caused by the red filter which contributes towards such improvements in fixation.