RESUMOInteração medicamentosa indesejável está entre as principais causas dos problemas relacionados aos medicamentos, podendo ocasionar prejuízos na recuperação da saúde do paciente. O objetivo foi investigar a ocorrência de interações medicamentosas na farmacoterapia dos idosos atendidos na Farmácia Básica de Santa Cruz do Sul -RS. Estudo transversal, com coleta de dados entre Agosto a Setembro de 2014, através de entrevista individual. As interações medicamentosas foram obtidas através do software Micromedex ® Solutions. Dos 204 regimes terapêuticos analisados, 54,4% continham pelo menos uma interação medicamentosa. A gravidade das interações encontradas foi: menor (n=26), moderada (n=160) e maior (n=45). O Ácido Acetilsalicílico teve a maior prevalência (23,8%) de interações, e Hidroclorotiazida foi o mais prescrito (18,6%). O manejo clínico mais indicado para as interações foi monitorização do paciente (73,6%). A identificação das interações permite tratamentos mais efetivos, menos complicações, racionalidade dos medicamentos, melhorias na qualidade das prescrições e na qualidade de vida dos pacientes. ABSTRACTThe undesirable drug interactions is among the main causes of the problems related to drugs and may cause losses in the recovery of the patient's health. The objective was to investigate the occurrence of drug interactions in the pharmacotherapy of the elderly attended in Basic Pharmacy in Santa Cruz do Sul -RS. Cross-sectional study with data collection from August to September 2014, through individual interviews. Drug interactions were obtained by Micromedex ® Solutions software. 54.4% of the 204 therapeutic regimens analyzed had at least one drug interaction. The severity of the interactions found was: minor (n = 26), moderate (n = 160) and major (n = 45). The Aspirin had the highest prevalence (23.8%) of interactions and Hydrochlorothiazide was the most prescribed (18.6%). The most appropriate clinical management of interactions was the patient's monitoring (73.6%). The identification of the interactions allows treatments more effective, fewer complications, rationality of drugs, improvements in the quality of prescriptions and in the quality of patients life.

The complexity of a pharmacological treatment can lead to a lack of adherence to the proposed treatment and consequently damage the recovery of the patient's health. The objective was to evaluate the complexity of the treatment regimen used by elderly patients attended in Basic Pharmacy of Santa Cruz do Sul, RS, and associated factors. I was done a cross-sectional study with data collection in the period from August to September 2014, through individual interviews with a semi-structured questionnaire containing sociodemographic variables, behavioral, health and pharmacotherapy variables. The therapeutic complexity index (TCI) was obtained by direct measurement of the necessary actions to administer the medicine. 300 elderly were interviewed; 76.7% were female, 70% aged 60-69 (± 6) years, and 77% had physician consultation in the last six months. The most cited diseases were hypertension (44.3%), depression (43%), high cholesterol (32%), diabetes (21%) and osteoporosis (20.7%). In the 15 days preceding the interview, the interviewers took a total of 1088 medicines (mean = 3.6 (± 1.74)). The TCI ranged from 1 to 30 (mean = 6.67 (± 5.35)) with statistically significant association (p < 0.05) with the female, referred diseases (diabetes, high cholesterol, osteoporosis, bronchitis, hypertension), take several medications at the same time and non-adherence to treatment. The evaluation of the complexity of pharmacotherapy is necessary and important for the restoration and maintenance of elderly's health. Simplifying treatment regimens can improve medication adherence and benefit on the outcome of therapy, allowing an understanding and a more accurate approximation of the elderly with their treatment.Keywords: elderly; pharmacotherapy; medication adherence RESUMO A complexidade de um tratamento farmacológico pode acarretar falta de adesão ao tratamento proposto e, consequentemente, prejuízos na recuperação da saúde do paciente. O objetivo foi avaliar a complexidade do regime terapêutico utilizado pelos idosos atendidos na Farmácia Básica de Santa Cruz do Sul -RS e os fatores associados. Foi feito um estudo transversal, com coleta de dados no período de Agosto a Setembro de 2014, por meio de entrevista individual com questionário semiestruturado contendo variáveis sociodemográficas, comportamentais, de saúde e da farmacoterapia. O índice de complexidade terapêutico (ICT) foi obtido por meio de medida direta das ações necessárias para administrar o medicamento. Foram entrevistados 300 idosos, sendo que 76,7% do sexo feminino, 70% tinham idade de 60 a 69 (± 6) anos e 77% realizaram consulta médica nos últimos seis meses. Dentre as doenças referidas destacaram-se hipertensão (44,3%), depressão (43%), colesterol elevado (32%), diabetes (21%) e osteoporose (20,7%). Nos 15 dias anteriores à entrevista, foram utilizados 1088 medicamentos pelos idosos entrevistados [média = 3,6 (± 1,74)]. O ICT variou de 1 a 30 [(média = 6,67 (± 5,35)], apresentando associação estatisticamente significativa (p < 0,05) com o sexo feminino...

Background People with disabilities (PWD) living in rural areas are subject to various vulnerabilities and inequalities that add to the barriers faced due to disabilities. The study aims to identify the sociodemographic profile of PWD living in rural areas of southern Brazil. Methods Quantitative study and a section of the ongoing research 'Work, Inclusion and Health Problems of People with Disabilities in Rural Scenario: an analysis in the southern region of Brazil', from the Health Studies and Research Group of the University of Santa Cruz do Sul (UNISC)/Brazil. Conducted in six municipalities in the state of Rio Grande do Sul with 37,333 inhabitants, 84.3% in the rural area and 32.7% are PWD. The first stage of data collection occurred through the survey of PWD older than 18 years and the second stage through a questionnaire. For statistical and descriptive analysis, the Software SPSS 22.0 was used. The research comply with the Resolution 466/2012 and the Ethics and Research Committee of UNISC approved it under nº. 341658. Results The subjects represent 1.33% of the total population and 1.57% of the rural population of the 6 municipalities. Data were compiled from 495 subjects and 22 of them answered the questionnaire. It was identified 271 subjects from three municipalities, 52.8% were male. The deficiencies were 39.1% intellectual, 25.5% physical, 18.1% auditory, 8.9% visual and 8.6% multiple. Of the 22: 12 were men; 12 were between 18 and 35 years old; 16 with white skin color; 11 did not complete elementary school; 13 with intellectual/mental disabilities; in 18 subjects the deficiencies are of congenital origin; 17 never worked; 5 have already worked and one still work. Conclusions The study shows that the PWD are mostly young men with low level of education, who did not perform work activity and with congenital mental disabilities. Such data are important for planning public policies that are more effective. Key messages Identifying data and the profile of PWD in rural contexts contributes to the development of public policies in the municipalities investigated and can contribute to other locations and regions. People with disabilities (PWD) living in rural areas are subject to various vulnerabilities and inequalities that add to the barriers faced due to disabilities.

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The study analyzed the relationship between the variables of the sociodemographic, clinical and occupational profile of farmers exposed to pesticides undergoing treatment at a reference unit in oncology in southern Brazil with the presence of hematological neoplasms. 72 farmers participated, mostly female, elderly, low education level and rural residents. Leukemia, non-Hodgkin's lymphomas and multiple myeloma prevailed. There was statistical significance between the variables tobacco cultivation and health region with the existence of the disease and when comparing the initial age in agriculture and the daily working hours with the use of different types of pesticides, pointing to a possible relationship between these variables with the presence of hematological neoplasms. Changes in lifestyle and work become important for promoting the health of the rural population.