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Since March 11, coronavirus infection has become an intercontinental problem – a pandemic has developed.Ukraine (until December 2019) ranks 17th in the world in the number of Covid-19 cases. Although according to statistics, the children are the least vulnerable group for coronavirus infection, unfortunately, severe and serious complications such as pneumonia, Kawasaki disease and Kawasaki-like syndrome, Multisystem inflammatory syndrome in children, toxic shock syndrome, myocarditis occur in children, too. As of the end of November, according to the Ministry of Health in Ukraine, 732,625 cases of coronavirus were laboratory- confirmed, including 13,720 children. According to the Lviv Regional Laboratory Center of the Ministry of Health, in the Lviv region since the beginning of the Covid-19 pandemic, among 46078 of all infected were about 5-6% of children. To analyze clinical, laboratory features of severe coronavirus infection complicated by bilateral pneumonia with acute respiratory distress syndrome (ARDS) in a three-year-old girl who was on V-V ECMO for one week and mechanical ventilation of the lungs for 28 days. The diagnosis was confirmed by detection of SARS-CoV-2 virus RNA by PCR, X-ray and ultrasound examination of the lungs. The disease had a dramatic course but a successful outcome. Life-threatening conditions associated with COVID-19 in children are much less common than in adult patients. However, in some cases, when critical hypoxemia is not eliminated by traditional methods of respiratory support, ECMO can become a life-saving technology and with its timely usage in pediatric patients.

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Adenocarcinoma is the most common type of bronchogenic carcinoma in pediatric patients. It often has a poor prognosis, and stage 4 of the disease is observed in approximately 50% of the diagnosed cases. 1 We present the case of a 17-year-old female patient with a complaint of unproductive cough for 4 months, which intensified during exercises and air temperature changes. Intrusive cough, increased fatigue, and appetite and weight loss were observed. Chest X-ray revealed a right-sided pleural effusion. Drainage of the right pleural cavity was performed and Mycobacterium tuberculosis (Mbt) was detected in the exudate using polymerase chain reaction (PCR).Complete blood count (CBC): hemoglobin Z 133 g/L, red blood cells Z 4.0 Â 10 12 /L, white blood cells Z 6.9 Â 109/L, eosinophils Z 2%, neutrophils Z 72%, lymphocytes Z 15%, and erythrocyte sedimentation rate Z 58 mm/h.Due to an Mbt-positive PCR, the patient received tuberculosis treatment according to the protocol: isoniazid, rifampicin, streptomycin, B vitamins, and glucocorticoids. Nausea and vomiting appeared a month and a half after treatment initiation. These complaints were treated as pharmacological side effects and basic therapy was discontinued. Two weeks later, signs of central nervous system (CNS) damage developed (headache, insomnia, and meningeal symptoms), and brain magnetic resonance imaging (MRI) with chest computed tomography (CT) were performed (Fig. 1).MRI conclusion: diffuse lesions of the brain parenchyma and cerebellum of parasitic origin (neurocysticercosis).According to MRI and CT results, a differential diagnosis between neurocysticercosis, pulmonary tuberculosis, and lung tumor was made.