The objective of the paper was to show the relationship between cerebral palsy and epilepsy and to determine the occurrence, associated factors, nature and prognosis of epilepsy in children with cerebral palsy.

The aim of the study was to define factors that can be used to distinguish migraine headaches from primary non-migraine headaches. Specific characteristics of headaches were analysed in 30 636 children aged 3–17; 18.97% had recurrent primary non-migraine headaches, whereas 8.63% had migraine headaches. Migraine attacks follow identical patterns (94.9%): occurring monthly (78.0%), occurring in morning hours (58.5%), lasting for several hours (45.1%) and ending after sleep (76.7%). Nausea, vomiting impulse and vomiting are basic present elements of migraine attacks in children. Canonical discriminate analysis defined the following statistically significant factors, which can distinguish migraine headaches from primary non-migraine headaches in children: relief after sleep (0.945), vomiting impulse (0.945), photophobia (0.523), nausea (0.379), phonophobia (0.354) and vomiting (0.330).

Half of the reported children having Ohtahara syndrome die in infancy. Anticonvulsant helps little in controlling the seizures and halting the deterioration of psychomotor development. Severe psychomotor retardation is the rule. With time, the disorder may evolve into West syndrome or partial epilepsy. Psychomotor development may be slightly better if the infants do not develop West and later Lennox-Gastaut syndrome.

The aim of the study was to determine recurrent headache (migraine and non-migraine) heritability, among the twin pairs. Headache hritability was investigated among 396 twin pairs (42.4% monozygotic and 57.6% dizygotic) aged 3 to 21 years, on north part territory of Serbia-Vojvodina, during the 20 years period. Within the group of tested twin persons, 30.2% had recurrent headaches, 9.2% migraine headache and 21% other recurrent non-migraine headaches. Heritability quotient of all recurrent headaches was 0.3882. For non- migraine headaches heritability quotient of 0.2286 confirmed that the external factors influence is higher than heritability. Migraine headache heritability quotient 0.8598 clearly proved the heritability of the migraine headache. Both, correlation and determination quotient of the migraine headache of all the twins (r12 0.7498; r21256.12%), monozygotic (r120.8458; r1271.54%) and dizygotic (r120.6342; r21240.22%), show high degree of migraine headache twin siblings dependence, and higher correlation and significance of the difference with monozygotic twins

The aim of this research was to determine risk for family appearance of the recurrent headache (non-migraine and migraine). The recurrent headache can be understood as being a heterogeneous state, consisting of some more, still not found, hereditary disposition factors which altogether, interacting with surrounding factors give the recognizable clinical picture. The current heredity concept suggests multifactor heredity. The research was conducted in Vojvodina, the Northern Province of Serbia. The population of Vojvodina is around 2 million people belonging to more than 20 different ethnic groups. During the 20 years period (1988-2008), 30363 children aged 3 to 17 years were tested, independent of the place of birth. The presence of headaches similar to those tested was compared among all the members of the family within three generations. Positive family data of the recurrent headaches was detected among 98,6% children with migraine headaches, 64,7% children with non- migraine headaches, and 32,4% children without recurrent headaches. The relation among the members of the nuclear family (contingency quotient of 0,429) is significantly stronger than the relation to the members of wider family (contingency quotient of 0,338). The probability of a child having the migraine headache, and not the non-migraine one, is 0,664 for a mother, 0,644 for a father, 0,411 for a father`s mother, - 0,175 for a mother`s mother, 0,165 for a mother`s father, and - 0,102 for a father`s father having similar recurrent headaches