Introduction: Barrett's esophagus (BE) with low-grade dysplasia represents a risk of progression towards esophageal adenocarcinoma. Hybrid-APC turns out to be an effective, safe, easy to use and relatively low-cost technique to stop this progression. Aims: to describe the therapeutic response of Hybrid-APC in patients with low-grade dysplasia in Barrett's esophagus. Method: an observational, descriptive investigation of a series of cases was carried out at the National Center for Minimal Access Surgery between December 2018 and December 2020. Twenty patients with BE histologically classified with low-grade dysplasia were included. Ablation with Hybrid APC was applied, and endoscopy was performed three and six months after the end of the treatment. The therapeutic response was evaluated through histological remission and the presence of complications. The information was processed in the statistical program SPSS, version 21. Results: mean age 50.5 (range 27-81 years). 55% (11) are male. Eighty-five percent were asymptomatic and 90% had circumferential BE. 55% (11) required a HybridAPC session. With an average of 1.4 sessions, macroscopic and histological remission without dysplasia was achieved at three and six months in 90% (18/20) and 92.8% (13/14) of the patients respectively, without witnessing complications. Conclusions: endoscopic treatment with the Hybrid-APC has a good therapeutic response, with a good histological remission and without complications, in patients with low-grade dysplasia in BE.

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To assess the role of 111In antimyosin antibody (AbAm) in the delineation of myocardial damage following coronary bypass surgery, we studied 51 consecutive patients who underwent coronary surgery, 27 of whom had a history of prior myocardial infarction. All patients underwent a diagnostic protocol comprising: (1) 99Tcm pyrophosphate (PYP) and AbAm injection 48 h after surgery (AbAm imaging 24 and 48 h post-injection) (myocardial/background and myocardial/lung ratios were obtained respectively from the computer image); (2) Radioimmunoassay (RIA) serum CK-B levels from samples obtained immediately before surgery, and 24 and 48 h later; (3) clinical and ECG follow-up. Twenty-five patients showed positive AbAm studies, 10 had positive PYP images, and 21 had CK-B levels above normal limits at 24 h. One patient with abnormal AbAm, PYP and CK-B studies had new Q waves on the ECG after surgery. This patient was considered to have sustained a peri-operative myocardial infarction. The large number of positive AbAm studies probably reflects myocardial damage frequently associated with coronary bypass surgery.