Collagens and hyaluronic acid have long been used in pharmaceuticals and food supplements for the improvement of skin elasticity and hydration. These compounds provide the building blocks of the skin. Ovoderm is an oral supplement obtained from eggshells that contains naturally occurring collagen and glycosaminoglycans, such as hyaluronic acid. We evaluated the efficacy of Ovoderm on skin biophysical parameters related to cutaneous aging such as elasticity, hydration, and pigmentation. Two pilot studies were run to assess the effect of daily oral supplementation with 300 mg Ovoderm on skin parameters. The first consisted of a self-assessment questionnaire intended to perform an assessment on skin, hair, and nail health after 50 days of treatment. The second measured the effect of 5-week treatment on hydration by corneometry, on elasticity with the cutometer, and on pigmentation with the mexameter. In the pilot study 1, participants were predominantly satisfied with the effects obtained on general face (100% volunteers satisfied) and body (94% volunteers satisfied) skin condition and skin properties (100% volunteers satisfied with facial skin softness, 94% with facial skin hydration, and 89% with body skin hydration) and partly with effects on hair (67% volunteers satisfied) and nail (50% volunteers satisfied) condition. The study 2 revealed a statistically significant improvement in skin elasticity (12% increase, p =.0136), a tendency to reduce skin pigmentation (5% decrease), and no significant change in skin hydration. Our study reflects that oral supplementation with Ovoderm is efficacious to reduce the gradual loss of skin elasticity characteristic of aged skin, which helps to improve the appearance of the skin.

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The eggshell membrane has shown a positive effect on joint pain relief. In this study, several tests have been performed to measure the effect of Ovomet® supplementation on subjective perception and biomechanical variables to crossfiters before and after 50 days of administration.Pain perception questionnaires were performed in order to assess and demonstrate the protective or potentiating of Ovomet® effect on athletes' joints. In addition, we measured biomechanical variables such as muscle strength and power in knee extension, linear stiffness of the Achilles tendon (AT) by ultrasound, muscle stiffness through sensor in two different manoeuvers.Of all the biomechanical variables, the measurement of tendon stiffness by ultrasound, proves to be a useful tool to study the factors that can affect the joints, like our object of study, the effect of joint supplementation on athletes.

According to previous published works, the eggshell membrane has shown a positive effect on the joint pain relief. In this study, several tests were performed to measure the effect of Ovomet ® (eggshell membrane) supplementation on the subjective perception and biomechanical variables in institutionalized patients of advanced age before and after 50 days of 300 mg Ovomet ® administration. The aim was to demonstrate and verify the protective and regenerative effects of Ovomet ® on the joints. To measure this effects some pain perception questionnaires were performed and biomechanical variables such as muscle strength and power in knee extension, linear stiffness of the Achilles tendon (AT) by ultrasound, muscle stiffness by means of sensor in two different manoeuvers were carried out. In conclusion, the daily intake of 300 mg Ovomet ® during 50 days showed a positive effect on the linear stiffness of the AT in institutionalized elderly patients showing the usefulness of the echography technique of linear stiffness of the AT to study the factors that increase the protection capacity of the joints.