The Plusoptix is a useful objective screening instrument, but still has low specificity for detecting amblyopia risk factors in the paediatric population.
Purpose To evaluate the efficacy of PVEP, standard automated perimetry, short‐wavelength automated perimetry, CS, stereoacuity in detecting subclinical visual impairment in patients with multiple sclerosis (MS) and no history of optic neuritis.
Methods Twenty‐seven MS patients (average age 33.81±9.33 years) underwent PVEP with 60 and 15‐minute arc check sizes, SAP (Humphrey 750‐II, SITA standard strategy), SWAP (program central 30‐2), CS, Stereoacuity by RSA test. They were age and sex matched with twenty seven normal subjects.
Results Stereoacuity was significantly reduced in MS group compared with controls. (p=0.007). P100 latency time for both check sizes was significantly prolonged in MS group compared with controls (p=0.005). P100 amplitude significantly reduced in MS group compared with controls (p<0.001). When comparing MS patients with the control group significant differences were found for SAP MD, SWAP MD, SAP PSD, SWAP PSD (p<0.001). By considering predefined criteria, asymptomatic MS patients have shown abnormal stereoacuity in 22.2%, abnormal VEP in 40.7%, abnormal CS in 37%, abnormal SAP in 44% and abnormal SWAP in 37% of patients.
Conclusion Our results concluded the probable presence of subclinical visual impairment among MS patients without optic neuritis history and no visual symptoms. The Pattern VEP and perimetry test together are useful choices in the regular assessment of these patients.
Objective To evaluate the safety, efficiency, short term stability, and sensory results of photorefractive keratectomy (PRK) in anisometropic in non-compliant children with correction. Methods Twelve eyes of 12 children with an age range: 6–17 years and anisometropic amblyopia who underwent PRK under general anesthesia to correct the dioptric difference between the eyes were included in this study. A complete ophthalmic assessment including refractive status, uncorrected and corrected distance visual acuity (UDVA & CDVA), and binocular vision status using the Worth 4-dot test and stereopsis were performed before and 1, 3, 6, and 12 months after PRK. Results The mean preoperative CDVA was 0.34 ± 0.24 LogMAR which showed a statistically significant improvement at 12 months (0.20 ± 0.19, p = 0.024) after surgery compared to the preoperative assessment. (p = 0.003) The mean preoperative UDVA was 0.63 ± 0.24 LogMAR that increased to 0.44 ± 0.24, 0.32 ± 0.16, 0.25 ± 0.19, and 0.25 ± 0.19 LogMAR at 1, 3, 6, and 12 months after PRK, respectively. One to three lines improvement in UDVA and CDVA was seen in 10 (83.4%) and 8 eyes (66.7%); while one line UDVA and CDVA loss was seen in one (8.3%) and one (8.3%) eye and unchanged UDVA and CDVA was seen in 1 (8.3%) and 3 eyes (25%), respectively. The mean preoperative stereoacuity was 341.9 ± 245.7 s of arc, which significantly improved to 166.6 ± 87.5 s of arc 12 months after PRK. (p = 0.012) Conclusion PRK was an effective surgical alternative to improve visual acuity and stereopsis in anisometropic children who did not cooperate with conventional methods of amblyopia therapy.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.