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New Hepatoprotective Saponins, Bupleurosides III, VI, IX, and XIII, from Chinese Bupleuri Radix: Structure-Requirements for the Cytoprotective Activity in Primary Cultured Rat Hepatocytes.-The 11-oxygen function, the 16β-hydroxyl group and the 3-O-diglycoside moiety are found to be essential to exert the cytoprotective activity. -(MATSUDA, H.; MURAKAMI, T.; NINOMIYA, K.; INADZUKI, M.; YOSHIKAWA, M.; Bioorg. Med.