Perovskite quantum dots (PeQDs) have been regarded as an alternative to traditional phosphor color converters in the backlit display to improve the color gamut and rendition of LCD. However, the pending barriers of aggregation quenching and structure instability are hindering their practical applications. Herein, high-quality CsPbX3 (X = Br, Br/I) PeQDs were in situ precipitated inside glass to produce nanocomposites with superior optical performance and stability. The highest photoluminescence quantum yield (PLQY) of ∼100% for CsPbBr3@glass is ascribed to the elimination of the inner filter effect via a physical dilution approach to restore its apparent value to an intrinsic one, and the exceptional photostability and water/heat resistance are benefited from their effective isolation from the external environment by the surrounding glass network units. Employing the PeQDs@glass@PDMS monolithic film, a high-performance backlit LCD was designed, and its color gamut reached 152% of commercial LCD and 103% of NTSC, demonstrating a great potential in the optoelectronic industry.
Modern structures on aircraft make increasing use of large-scale composite structures. Quantitative damage monitoring for composites, including damage occurrence, number, localization, and size estimation, will help reduce maintenance costs, improve fleet management efficiency through condition-based maintenance, and potentially more rapidly enable new material systems and structural concepts by integrating health monitoring into the design itself. With the advantage of easily interpretable, intuitive, and accurate imaging result, the delay-and-sum imaging algorithm is frequently researched and applied to damage monitoring. However, when it is applied to multidamage monitoring in large-scale composites, the consumed time and computation resource are too much for pixel value calculation. Besides, due to the material anisotropy and existence of bolt holes and stiffeners in the researched complex carbon fiber composite laminate, propagation mechanism of Lamb wave is quite complicated, which makes the conventional localization result not accurate by delay-and-sum algorithm according to the point with pixel peak value. What is more, the imaging quality is deteriorated with concurrence of multiple damages, and thus, quantitative damage information cannot be extracted. Hence, the damage index merging algorithm is introduced for quick damage identification and damage merging in every subarea divided by piezoelectric sensor array. The delay-and-sum imaging algorithm is performed afterward only in subareas identified with damages, which significantly improves the efficiency of damage imaging for large-scale composites. The nonlinear normalization of pixel values compensates the deterioration of multidamage imaging quality. Then, a weighted average algorithm is introduced for more accurate localization. A further damage size level estimation is realized with probabilities by extracting the image pixel peak value. Experiments with six damages simultaneously on the complex carbon fiber laminate verify the effectiveness of the proposed quantitative multidamage monitoring algorithm with localization error below 2 cm and correct damage number and size level estimation.
BackgroundSilver and photothermal therapy (PTT) have been widely used for eradicating the drug-resistant bacteria. However, the risks of excess of silver for humans and the low efficiency of PTT still limit their in vivo therapeutic application. Integration of two distinctive bactericides into one entity is a promising platform to improve the efficiency of antimicrobial agents.ResultsIn this study, a chemo-photothermal therapeutic platform based on polydopamine (PDA)-coated gold nanorods (GNRs) was developed. The PDA coating acquired high Ag+ ions loading efficiency and Cy5-SE fluorescent agent labeled glycol chitosan (GCS) conjugation (Ag+-GCS-PDA@GNRs). This platform became positively charged in the low pH environment of the abscess, allowing their accumulation in local infection site as revealed by thermal/florescence imaging. The loaded Ag+ ions was released in a pH-sensitive manner, resulting in selective Ag+ ions delivery to the abscess environment (pH ~ 6.3). More importantly, the ultralow dose of Ag+ ions could effectively damage the bacterial membrane, causing the permeability increase and the heat resistance reduction of the cell membrane, leading to the large improvement on bactericidal efficiency of PTT. On the other hand, the hyperthermia could trigger more Ag+ ions release, resulting in further improvement on bactericidal efficiency of chemotherapy. Combinational chemo-hyperthermia therapy of Ag+-GCS-PDA@GNRs could thoroughly ablate abscess and accelerate wound healing via a synergistic antibacterial effect.ConclusionsOur studies demonstrate that Ag+-GCS-PDA@GNRs is a robust and practical platform for use in chemo-thermal focal infection therapy with outstanding synergistic bacteria ablating.Electronic supplementary materialThe online version of this article (10.1186/s12951-018-0348-z) contains supplementary material, which is available to authorized users.
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