Fifty patients with unexplained vertigo (36) or lightheadedness (14) are evaluated, all of whom had abnormal ENGs and normal audiograms. Five hour insulin glucose tolerance tests were performance on all patients, with insulin levels being obtained fasting and at one-half, one, two, and three hours. The results of this investigation were remarkable. Borderline or abnormal insulin levels were discovered in 82% of patients; 90% were found to have either an abnormal glucose tolerance test or at least borderline insulin levels. The response to treatment in these dizzy patients was also startling, with appropriate low carbohydrate diets improving the patient's symptoms in 90% of cases. It is, therefore, apparent that the earliest identification of carbohydrate imbalance with an insulin glucose tolerance test is extremely important in the work-up of the dizzy patients.
Samples of blood, anticoagulated with EDTA, from 11 patients with psoriasis and 11 individuals without psoriasis were analyzed for their polyamine content. The average spermidine level in patients with psoriasis was approximately twice that of the controls and the average spermine level was three times that of the controls. The level of spermidine and spermine in the skin of two patients with psoriasis were significantly depressed as compared to those of controls.
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