Objective Nipple-sparing mastectomy (NSM) has been traditionally used in selected cases with tumor-to-nipple distance > 2 cm and negative frozen section of the base of the nipple. Recommending NSM in unselected populations remains controversial. The present study evaluated the oncological outcomes of patients submitted to NSM in an unselected population seen at a single center. Methods This retrospective cohort study included unselected patients with invasive carcinoma or ductal carcinoma in situ (DCIS) who underwent NSM in 2010 to 2020. The endpoints were locoregional recurrence, disease-free survival (DFS), and overall survival (OS), irrespective of tumor size or tumor-to-nipple distance. Results Seventy-six patients (mean age 46.1 years) (58 invasive carcinomas/18 DCIS) were included. The most invasive carcinomas were hormone-positive (60%) (HER2 overexpression: 24%; triple-negative: 16%), while 39% of DCIS were high-grade. Invasive carcinomas were T2 in 66% of cases, with axillary metastases in 38%. Surgical margins were all negative. All patients with invasive carcinoma received systemic treatment and 38% underwent radiotherapy. After a mean of 34.8 months, 3 patients with invasive carcinoma (5.1%) and 1 with DCIS (5.5%) had local recurrence. Two patients had distant metastasis and died during follow-up. The 5-year OS and DFS rates for invasive carcinoma were 98% and 83%, respectively. Conclusion In unselected cases, the 5-year oncological outcomes following NSM were found to be acceptable and comparable to previous reports. Further studies are required.

RESUMOGravidez abdominal é uma forma rara de gravidez ectópica com elevada morbidade e mortalidade para a mãe e o feto. O diagnóstico onde o acompanhamento pré-natal é precário. Neste estudo, os autores apresentam o caso de uma paciente de 40 anos, atendida em ou secundária segundo sua origem. As principais complicações maternas são sangramentos graves, fístulas intestinais e sepse. O feto pode apresentar malformações como assimetria craniofacial, deformidade de membros e sistema nervoso central. Quando realizado o diagnóstico precoce com menos de 20 semanas, pode ser orientado a interrupção da gestação ou um parto precoce, com Palavras-chave: Gravidez abdominal. Nascimento a termo. Gravidez ectópica. ABSTRACTAbdominal pregnancy is a rare form of ectopic pregnancy with high mortality to both mother and fetus. The diagnosis can be hard due the presence of symptoms. The cases occur specially in centers with poor resources, and prenatal care is limited. At this article, the authors present the case of a 40 years old patient with abdominal pregnancy of 37 weeks and symptoms. The diagnosis was made previously to birth with ultrasound exam, where we found the presence of a healthy fetus externally to the uterus. A healthy newborn was delivered by abdominal birth. The main maternal complications are of limbs and central nervous system. When an early diagnosis is made, it may be advised to interrupt the pregnancy when it is less than 20 weeks old and an early delivery, at 34 weeks, when the diagnosis is made after 20 weeks gestation.