No abstract

HIV dan AIDS merupakan salah satu permasalahan di Indonesia. Berdasarkan data dari Kementerian Kesehatan RI sampai dengan maret 2017, sebanyak 407 kota/kabupaten dari  507 kota/kabupaten dan lebih dari 87 ribu orang mengidap AIDS. Berbeda apabila dibandingkan dengan provinsi-provinsi lainnya, Papua mengalami epidemi HIV meluas tingkat rendah dengan prevalensi HIV sebesar 2.3 %. Jumlah penderita HIV lebih banyak terjadi pada perempuan usia reproduktif dibandingkan pada laki-laki. Meskipun HIV tersebar meluas di kelompok populasi umum baik untuk laki-laki maupun perempuan, kegiatan seks komersial memberikan kontribusi yang besar terhadap epidemi di semua wilayah Papua. Tujuan penelitian ini adalah menganalisis karakteristik demografi ODHA Di Papua Sebagai Baseline Data Di Indonesia. Penelitian dilakukan di tiga wilayah di Papua yaitu Kabupaten Nabire, Kab./Kota Jayapura, dan Kab. Jayawijaya dengan jumlah responden sebanyak 264 orang. Dari hasil penelitian yang dilakukan didapatkan hasil terdapat perbedaan karakteristik demografi ODHA di tiga wilayah Papua (Kabupaten Nabire, Kab./Kota Jayapura, dan Kab. Jayawijaya). Dari hasil penelitian dibutuhkan strategi penanganan ODHA yang berbeda di masing-masing wilayah.

BACKGROUND: Papua has a high cumulative number of HIV, which has expanded epidemic status with the most risk factors are heterosexuals. AIM: This study aims to determine factors associated with HIV disease progression include host and viral factors. METHODS: Eighty-four subjects recruited in Rumah Sakit Mitra Masyarakat (RSMM) VCT’s laboratory, interviewed with questionnaires and also did laboratory examinations. HIV-1 subtypes were identified using RT-PCR, nested PCR and sequencing. Then, CD4+ data is checked using PIMA Analyzer. Demographic and clinical data obtained from the patient's medical record. After collected, data were analysed using Fisher's exact test. RESULTS: The results showed two factors that influence the progression of HIV disease were HIV subtypes (p = 0.002) and Body Mass Index (p = 0.033). The HIV-1 subtype also correlated with CD4+ levels with a value of p = 0.04. CONCLUSION: HIV-1 subtype correlates with HIV progression, so it is necessary to develop HIV/AIDS management strategies and clinical counselling.

<p class="Englishversionofabstract">HIV-TB co-infection still becomes a health problem in Indonesia, including in Nabire district, Papua province, which has the highest number of cases. HIV and TB infections are closely related and affect the epidemiology of one another. This study aims to determine the profile description of HIV-TB co-infected patients in Nabire. This research is a descriptive study with a cross-sectional design on 90 people with HIV/AIDS selected consecutively. Data were analyzed univariately and presented in the form of a frequency distribution table. The results showed that of 55 HIV/AIDS co-infected TB patients, almost all (90.9%) were Papuan ethnic, 70.9% were female and aged 30 to 49 years (50.9%) with a mean of 31.309.36 years. The majority of HIV-TB co-infected patients were married (63.6%), holding secondary education (58.2%), working (67.3%), engaging in sexual activity after 17 years of age, only having one sexual partner, and did not use drugs or obtain blood transfusions. The clinical profile of HIV-TB patients showed that 67.3% of the patients were with baseline CD4 count ≤350 cells/mm3, 64.8% had CD4 count at the time of study &gt;350 cells/mm3, and viral load values fewer than 5000 copies/ml (87.3%). The therapy most widely received for patients with HIV-TB coinfection was the combination of ARV 3TC+EFV+TDF (76.4%). The most common clinical symptoms of HIV/AIDS patients were weight loss (56.4%), cough (40%), recurrent oral thrush (36.4%), chickenpox (32.7%), and tuberculosis lymph nodes (18.2%).</p>

No abstract