Poly(l-lactide) nano/micro fibres were produced using the electrospinning technique. The influence of solvent type and solution concentration on the morphology and structure of electrospun fibres were investigated. For this purpose, the electrospinning was performed using 2, 2, 2-trifluoroethanol (TFE) or dichloromethane (DCM) solvents at solution concentrations in a range of 5-9 wt-%. Morphological studies showed that versus DCMbased fibres with beaded structures and porous surface, when using TFE as a solvent, the uniform bead-free fibres with a smooth surface morphology were produced. Compared to DCM, the fibre diameter decreased using TFE as a solvent with lower vapour pressure while the crystallinity of the fibres increased. By increasing the solution concentration up to 9 wt-%, uniform fibres were produced with growing average diameters. Following these results, we conclude that varying the solution concentration and solvent type can modulate the final properties of electrospun fibres.

We investigated the electrochemical behavior of hemoglobin by glassy carbon electrode modified with Mn2O3-Ag nanofibers. The Mn2O3-Ag nanofibers were used as facilitator electron transfer between Hb and glassy-carbon-modified electrode. The Mn2O3-Ag nanofibers are studied by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The hemoglobin showed a quasireversible electrochemical redox behavior with a formal potential of −49 mV (versus Ag/AgCl) in 0.1 M potassium phosphate buffer solution at pH 7.0. The designed biosensor possesses good stability and reproducibility and achieves 95% of the steady-state current in less than five seconds.

In this study, it was aimed to present a nanofibrous scaffold with intentional roughness through a new electrospinning method called "mesh electrospinning method". Firstly, polyamide nylon 6 granules were dissolved in formic acid in different concentration (10-35 %w/v). A mesh template was placed between tip and collector in different distance (4 positions) in a conventional electrospinning line. The number of mesh layers and effects of processing parameters also considered. As it was expected, the results show that, increasing the polymer solution lead to increase fiber diameter, from 84 nm for 20% to 265 nm for 30%. The results showed that the layer just formed when the mesh was placed just on the collector. On the other hand, with increasing the number of mesh layers (1&3), roughness decreased (55-60%). It was also observed that the produced roughness is governed by the geometry of the mesh. To consider the ability for controlling the roughness, the produced roughness can be applied for drug delivery purposes transdermal drug delivery.