Background: Acute viral hepatitis (AVH) is a major public health issue throughout the world which affecting millions of people in every year. Clinical features of AVH may vary from asymptomatic to hepatitis, liver failure, cirrhosis and even cancer. The role of ultrasound in acute viral hepatitis (AVH) is limited to exclude the surgical causes of jaundice. A clear concept on the demographic and clinical profile of acute viral hepatitis may be helpful in the treatment procedure of this disease. Aim of the study: The aim of this study was to analyze the demographic and clinical profile of acute viral hepatitis patients based on sonographic findings. Methods: This was a prospective observational study which was conducted in the Department of Gastroenterology, US-Bangla Medical College & Hospital, Dhaka, Bangladesh during the period from January 2019 to December 2019. Along with other diagnosis, ultrasonography was considered as principal diagnosis for the inclusion of study subjects. As per the exclusion criteria of this study, patients detected to have HBV infection or with gall stone were excluded from the study. Sonographic data were collected and tabulated in an Excel sheet and was analyzed using IBM-SPSS version 22.0 to determine the means and proportions. Chi‑squared test was done to compare the ultrasound findings. P<0.05 were considered to indicate a statistically significant difference. Results: In this study, among majority of our participant’s spleen was found as normal in size which was in 96% cases. In only 4% cases splenomegaly was found. In the final ultrasonogram report of our participants we observed that, among a good number of patients, hepatomegaly, GBW thickening and contracted GB were found which were in 79%, 75% and 56% cases respectively. Besides these, porta nodes, splenomegaly and periportal cuffing were associated in 35%, 15% and 13% cases respectively. Conclusion: The ultrasonographic findings of hepatomegaly, contracted gallbladder, .......

Background: In Bangladesh, Acute hepatitis is seen sporadically round the year. On the other the other hand, the incidence of acute viral hepatitis E increases after floods as this allows sewerage contamination of piped and groundwater. Objective: In this study our main goal is to evaluate the demographic & Clinical Profile Analysis of Acute Viral Hepatitis E Patients in Bangladesh. Method: This prospective observational study was conducted in the Department of Gastroenterology, US-Bangla Medical College & Hospital during the period from July 2018 to June 2019, in Bangladesh. A total of 35 patients who were attending the Hepatology unit with acute viral hepatitis were included as the study population for this study. By enzyme-linked immunosorbent assay, all viral markers were tested. Results: Majority, 34.4% belong to 21-30 year’s age group, and 81.3% were male. Positive cases of Anti HAV IgM were 10% followed by Anti HEV IgM seen in 100%, however, none of the Anti HCV IgM seen in patients. Higher serum bilirubin was 8.82±5.65. Followed by Levels of aspartate aminotransferase (AST) was 1141.00±128.69, S.GPT ALT was 1380.75±751.28, S. Creatinine was10.00±18.33. Moreover, Prothrombin Time was seen longer in patients. Which means patient’s needs higher blood clotting time than usual. Conclusion: Acute viral hepatitis E is the leading cause of wide spectrum of liver disease in young male adults ranging from severe acute viral hepatitis, to decompensation of liver in cirrhotic in Bangladesh.

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Subclinical hypothyroidism (SCH) is a metabolic disorder with prevalence about 4-10% in general population. This study was conducted to observe the pattern of fasting lipid profile in SCH and to correlate the components of it with thyroid stimulating hormone and free thyroxin level. This cross sectional observational study included 31 newly diagnosed cases of SCH and 17 age and BMI matched healthy control subjects with normal thyroid function test. Fasting lipid profile was recorded and compared. TSH was significantly higher in SCH compared to controls (9.09±2.79 vs 2.31±0.92 μIU/ml; p=0.001). FT4 was comparable between the groups (1.17±0.18 vs 1.28±0.20 ng/dl; p=0.938). Significantly higher level of Total cholesterol and LDL-C were observed in SCH compared to controls (TC 194.77±29.70 vs 156.59±20.45 mg/dl; p=0.042 and LDL-C 124.81±27.85 mg/dl vs 88.59±18.41mg/dl; p=0.045 respectively). Triglycerides and HDL-C were comparable between the groups (TG 134.90±80.97 vs 118.12±49.14 mg/dl; p=0.171 and HDL-C 42.87±4.83 vs 44.47±5.66; p=0.633 respectively). TSH showed significant positive correlation with TC and LDL-C (r=0.591, p<0.001 and r=0.644, p<0.001 respectively), but not with TG or HDL-C (r=0.011, p=0.943 and r=0.115, p=0.435 respectively). FT4 only showed significant negative correlation with LDL-C (r=0.302; P=0.037) but not with TC, TG or HDL-C (TC: r=0.245, P=0.093; TG: r=0.121, p=0.411 and HDL-C: r=0.108, p=0.466 respectively). SCH is associated with raised TC and LDL-C. So patients with SCH are more vulnerable to develop future adverse cardio-metabolic complications. Faridpur Med. Coll. J. 2021;16(1):17-20

Background: Despite noteworthy socio-economic development and advancement of medical science, till now tuberculosis (TB) is considered a major public health problem. Although TB is a curable disease, still millions of people suffer from TB every year and a number of them die from this infectious disease. Now a day, the prevalence and nature of tuberculosis are not in a consistent stage. We need more current information regarding this issue. Aim of the study: The aim of this study was to determine the clinical profile of tuberculosis patients. Methods: This study was a prospective, observational study which was conducted in the Department of Internal Medicine, US-Bangla Medical College, Narayanganj, Bangladesh during the period from January 2020 to December 2020. In total 73 diagnosed patients with tuberculosis, treated in this hospital were selected as the study subjects. Properly written consent was taken from all the participants before data collection. All data were processed, analyzed, and disseminated by using MS Office and SPSS version 23 as per need. Results: In this study, the majority of the participants were from the>40 years age group. One-third (34%) of participants were primary level educated whereas one-fourth (25%) were secondary level educated. The majority (56%) of the patients were found as ‘never smokers’. ‘Never drinker’ (Alcohol) was found 86%. Among the highest number of participants, pulmonary Koch’s was found which was in 42%. Among all the participants, cough and fever were found as two more frequent symptoms which were found in 96% and 86% patients respectively. As the final treatment outcome, we observed, 42% (n=31) patients were fully cured. Treatment was continued on 53% of patients and 4% (n=3) death cases were found. Conclusion: According to the findings of this study we can conclude that fever and cough are the two most frequent symptoms in tuberculosis patients. Although the death rate among TB patients is not alarming, the .........