Background Patients increasingly express the desire to be involved in their treatment decisions, especially in critical situations, such as cancer chemotherapy that increase a doctor's responsibility toward fulfilling these needs. This process may require more than one meeting with the patient to meet their expectations and satisfaction levels. This study aimed to assess the satisfaction levels in cancer patients, who received chemotherapy, about their decision-making and if they were able to make this decision during the first meeting with their physicians.
Infants with trisomy 13 or trisomy 18 frequently suffer from cardiac anomalies. Our study aims to look at the impact of using cardiac surgery on mortality and functional outcome in patients with trisomy 13 and trisomy 18. A search for articles was done on PubMed, Scopus, Science Direct and CENTRAL databases; from inception until 30th October 2022. Quantitative analysis was done using Meta XL and Review Manager 5.4. A p=-value of 0.05 was adopted as the significance threshold. The database search yielded 1,127 articles but only 17 were included in this systematic review. This paper reports a total of 2,551 trisomy cases. 672 cases were T13, 1478 cases were T18 and 401 cases were undefined. The calculated Odds Ratio (OR) was 4.20 95%CI, 2.70 - 6.52], with a p-value < 0.00001. There was also the finding that cardiac surgery had a more positive impact on mortality and discharge outcomes for T18 patients than T13 patients. The difference, however was statistically insignificant. In conclusion, the use of cardiac surgery to manage T13 and T18 patients is plausible, but other factors like post-operative complications should be taken into account.
Placenta previa is an obstetric complication (OS) that traditionally shows painless vaginal bleeding in the third trimester secondary to a strange placentation close or covering the interior cervical OS. Due to the inherent risk of hemorrhage, placenta previa may cause serious morbidity and mortality to both the fetus and the mother. Recently there have been two defined types of placenta previa: complete, and marginal. We here review the complications, incidence, risk factors, and management options of placenta previa.
Infection with herpes simplex is a standout amongst the most well-sexually transmitted infections. As the infection is common in women of reproductive age it may be contracted and transmitted to the fetus amid pregnancy and the newborn. Herpes simplex virus is a significant cause of neonatal infection, which could lead to death or long-term disabilities. Infrequently in the uterus, as it happens frequently during the transmission delivery. The most serious danger of transmission to the fetus and the newborn happens in case of an early maternal infection contracted in the second half of pregnancy. The danger of transmission of maternalfetal-neonatal herpes simplex could be diminished by applying a treatment with antiviral medicines or depending on a caesarean section in some particular cases. The aim of this paper is to provide recommendations on the management of herpes simplex infections in pregnancy and approaches to decrease perinatal transmission of herpes simplex virus.
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