Gingival hypertrophy caused by certain drugs, including amlodipine, may occur in genetically susceptible individuals. There is no clear explanation for the exact mechanism behind gingival hypertrophy, but a multifactorial theory has been proposed that unifies the phenomenon. In addition to causing difficulty with speech and mastication, gingival hypertrophy also contributes to poor oral hygiene and unaesthetic appearance. We describe the case of a 54-year-old woman who developed gingival hypertrophy due to the long-standing antihypertensive medication amlodipine 5 mg taken twice daily for four years.
Obstructive sleep apnea (OSA) is characterized by repeated episodes of upper airway blockage and collapse during sleep accompanied by awakenings with or without oxygen desaturations. During obstructive sleep apnea events, the oropharynx in the back of the throat compresses, causing arousal, oxygen desaturation, or both, leading to fragmented sleep. The hyperplastic uvula is a common clinical finding in patients with obstructive sleep apnea. The various diagnostic and treatment modalities of obstructive sleep apnea are discussed in this article.
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