The objective of this study is to evaluate the antioxidant and hepatoprotective activity of aerial part and seeds of Coriandrum sativum plant against Lambda cyhalothrin insecticide.  Male Wistar Albinos rats were randomly divided into control, LCT, CsA, CsS, CsS+LCT, CsA+LCT groups, after 90 days of treatments Biochemical, some oxidative stress parameters, and histopathology of liver tissue were evaluated. Total polyphenol content in aerial part and the seed extract estimated at 9.29 and 14.64 mg EAG / mg of extract and IC50 for an antioxidant activity equal to 19.38 and 22.62 mg/ml respectively. The obtained results revealed that rats received Lambda cyhalothrin insecticide showed a significant change in enzymes activity (AST, ALT, ALP and c-GT) and Glutathione (GSH) in liver. Meanwhile content of hepatic Malondialdehyde (MDA). Histopathology examination of liver revealed that Coriandrum sativum attenuate the incidence of liver lesions triggered by Lambda cyhalothrin intoxication. Therefore, the results of this study show that Coriandrum sativum can be proposed to protect the liver against Lambda cyhalothrin induced oxidative damage in rats, and the hepatoprotective effect might be correlated with its antioxidant and free radical scavenging effect. Keywords: hepatoprotective, antioxidant, Coriandrum sativum L., Lambda cyhalothrin, Oxidative stress.

Plants have been a source of important chemical compounds that can be used for treatment of different disease. Natural products in plants also are a source of active compounds and can be considered an alternative to synthetic molecules with high antioxidant potential. Objective of this study was to determine the antioxidant and antibacterial potential of Ephedra alata extract. Methods: Phytochemical values namely, total phenolic, DPPH radical scavenging effect were studied by established methods. Antimicrobial properties of Ephedra alata was tested using cup-plate diffusion method and disc diffusion. Results showed numerous secondary metabolic products including in plant Ephedra alata extract such as Flavonoids, Saponins, Tannins were detected. And other metabolic products such as Steroids and Cardinolids are absent.  The yield for the aqueous extract was 9.89%. However, the polyphenols extract content was equal to 0.004243 (mg GAE/ml extract. Effectiveness of antioxidant plant using DPPH free root was estimated at IC50= 0.901 mg/ml for aqueous extract. In antibacterial screening, the extract showed antibacterial power with zone of inhibitions compared to positive controls Penicillin against multi-resistant germs such as: Pseudomonase aeruginosa and Serratia fonticola responsible of many infectious. Growth inhibition varies with bacterial species and concentration of Ephedra alta extract.

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Among the heavy metals most commonly found on land, lead is a strongly represented pollutant in soil and sediments. It is easily absorbed and accumulated in different parts of plants. On the macroscopic scale, lead causes unfavorable effects on plants. First and in the event of excess, it may exert toxicity affecting several stages of germination development in leaf formation and root elongation in the early stages of development. The effect of lead on two varieties of durum wheat Triticum durum cv Gta and Vitron have been analyzed on germination under laboratory conditions. The objective is to determine the influence of lead on (i) germinal parameters and (ii) the stress physiological markers. The experiment was set up in a completely randomized design with 3 replications of 20 seeds per variety, including 4 concentrations of Pb(NO 3 ) 2 (0, 320, 430 and 660 ppm) on the germination. Average ambient temperature was 22°C, the humidity was 32% and photoperiod light/dark was 16/8 h. The obtained results showed a real sensitivity of germination to lead. Indeed, it was noted a total absence of germination of the two varieties in all seeds treated with the highest concentration. The treatment of seeds by the increasing doses of lead decreased the germinative faculty considerably, the content of pigments and disrupted the cellular metabolism, the proteins, the proline and glutathione levels. These results indicated that lead stress caused a decrease in germinal parameters and significant impairment of cell biochemical markers. Such effect was inversely proportional to the doses used. It was also noted that the Gta variety was less sensitive to lead toxicity than Vitron.