Pasien diabetes melitus (DM) cenderung menujukkan percepatan proses aterosklerotik dan akibatnya risiko penyakit kardiovaskular lebih tinggi seperti penyakit jantung koroner.DM sering dipersulit dangan komorbiditas lainnya yang berkontribusi terhadap peningkatan risiko penyakit kardiovaskular (seperti, hipertensi, penyakit ginjal kronis, dan dislipidemia).  Kontrol glikemik yang tidak adekuat atau terjadinya resistensi insulin mengaktifkan saraf simpatis, yang memicu MBPS berlebihan pada pasien DM.MBPS berlebihan terlibat dalam patogenesis kejadian kardiovaskular pada pagi hari  dengan mencetuskan stres hemodinamik. Tujuan umum dari penelitian ini adalah untuk mengetahui hubungan antara  pengendalian glukosa darah dan MBPS, serta hubungan antara MBPS dan kejadian penyakit jantung koroner pada pasien diabetes melitus di Rumah Sakit Umum Cut Meutia. Penelitian ini merupakan penelitian observasional analitik dengan rancangan potong lintang (cross sectional). Sumber data dalam penelitian ini diperoleh dari data primer berdasarkan hasil identifikasi karakteristik pasien, pengukuran morning blood pressure surge, kadar gula darah puasa dan pemeriksaan EKG. Hasil penelitian menunjukkan sebesar 75% responden pada penelitian ini (n = 32) memiliki kadar gula darah puasa yang tidak terkontrol, 53,1% responden dengan morning hypertension dan 62,5% responden mengalami Penyakit Jantung Koroner (PJK).  Pada analisis bivariat, hasil menunjukkan terdapat hubungan antara kontrol gula darah puasa dengan morning hypertension (p value = 0.024%). Secara umum terdapat hubungan timbal balik antara DM dengan hipertensi.

Background: Various efforts have been made to accelerate the wound healing process in white rats, one of which is using Chromolaena odorata. The leaves contain tannins, phenols, flavonoids, saponins, and steroids, which accelerate the wound healing process. The purpose of this study was to determine the effect of Chromolaena odorata leaf jelly extract on the wound healing process in the inflammatory and proliferative phases in white rats microscopically (Rattus norvegicus).  Methods: A total of 27 healthy adult male white rats aged 3-4 months old were given open wounds on the back measuring 2x2 cm. The rats were then divided into four groups, a group administered with jelly without Chromolaena odorata leaf jelly extract (P0) and groups administered with Chromolaena odorata leaf jelly extract with concentrations of 10% (P1) and 30% (P2), respectively. Chromolaena odorata leaf jelly extracts were given daily by rubbing them on the wound surfaces. Skin biopsies were collected and evaluated histopathologically on days 3, 7, and 14 post-treatment. The histological assessment of wound healing was based on epithelialization and collagen density using Nagaoka criteria. The data were analyzed by analysis of variance (ANOVA) and continued with the Duncan test. Results: The Duncan test results showed that the mean score of the degree of epithelialization and collagen density of wound tissue on days 7 and 14 was significantly higher in the P2 group compared to the P0 and P1 treatments, while the P1 group was not significantly different from P0.  Conclusions: In conclusion, the administration of Chromolaena odorata leaf jelly extract could accelerate the degree of epithelialization and collagen density in the wound healing process of the inflammatory and proliferative phases of white rats (Rattus novergicus).

Aloe vera have active chemicals substances including saponins, tannins, flavonides, and polyphenols. Saponin takes a role as a disinfectant, so it is normally effective for healing any open wounds, while tannins have ability to be an antiseptic. This study aims to see how the effect of the Aloe vera gel on wound collagen, and too inspect which is the most effective concentration of the Aloe vera gel in the formation of wound collagen in wistar strains (Rattus novergicus) rats. This study uses a post-test only method with control group design. The subjects of this study were 28 male Wistar rats (Rattus novergicus). The subjects were divided into 4 groups consisting of 1 negative control group and 3 treated groups, the control group was not given any treatment, while the treated group was given the Aloe vera gel with each concentrations of 12.5%, 25%, and 50% respectively. The experiment was started by making a wound on the back of the rat which then be followed by applying the gel to the wound for 14 days. The results showed the group with the 50% Aloe vera gel treatment had the best collagen formation, followed by a concentration of 25%, 12.5%, and the control group. Therefore, the used of Aloe vera has given good change in scar collagen, and the best scar collagen can be viewed in the group with 50% concentrate of Aloe vera.

Kebutuhan listrik meningkat lebih cepat daripada pertumbuhan penduduk. Hal ini disebabkan karena peningkatan akan kebutuhan listrik akibat pertumbuhan sektor-sektor lainnya, seperti sektor industri, sektor ekonomi dan sebagainya. Banyaknya potensi sumber energi di sekitar kita belum dimanfaatkan dengan baik. Saluran irigasi yang selama ini hanya digunakan untuk membawa air bagi pemenuhan kebutuhan air di sektor pertanian perlu dilakukan inventarisasi sehingga didapatkan lokasi-lokasi yang memiliki potensi pembangkit listrik. Analisis pengamatan pada DI. Way Umpu baik debit yang akan digunakan untuk memenuhi kebutuhan pertanian maupun kecuraman aliran pada saluran irigasi. Lokasi yang dapat dijadikan pembangkit listrik/ listrik tenaga air mini (PLTM) pada DI. Way Umpu, sehingga air dapat memberikan nilai tambah. Hasil Analisis Terdapat Potensi Listrik Tenaga Air pada DI. Way Umpu dengan memanfaatkan air yang ada dan memodifikasi saluran irigasi Primer Neki. Dari 8 (delapan) alternatif yang dianalisis, dengan menggunakan asumsi Kehilangan Tinggi 10 % dari total tinggi jatuh,Efisiensi Pembangkit 0,80 maka diperoleh potensi energi listrik yang dihasilkan. Disarankan perlu kajian hidrolika dan kajian ekonomi sehingga didapat alternatif yang dapat dilaksanakan, diperlukan pembahasan kepemilikan aset dan metode pemeliharaan bersama serta diperlukan kajian untuk saluran Rantau Tamiang dan Suplesi Way Besa

The aims of this study are to find out the healing process of Priapism in Patients Chronic Myeloid Leukemia. This study used one case of patient which has some complaint, The patients is man with age 29 years old, The patient complained of an enlarged left stomach since 4 months and became heavy in the last 2 weeks, On vital sign examination, compos mentis awareness was found with blood pressure 110/70 mmHg, pulse 80 times per minute, respiratory rate 20 times per minute and temperature 37oC. On the visual analogue scale (VAS) examination showed a value of 4-6 (moderate pain). The result shows that CML is a hematological malignancy characterized by the Philadelphia chromosome and detected clonal expansion of hematopoietic stem cells from ABL BCR examination on chromosomes 9 and 22 which is characterized by an increase in the number of leukocytes with or without enlargement of the spleen. One of the complications of CML is priapism which occurs due to hyperleukocytosis which causes an increase in the viscosity of the blood and this is a major cause of complications of vascular obstruction. Priapism in CML is classified as low-flow (static / ischemic) caused by venocclusiveness which must be treated immediately to restore blood flow to the cavernous corpora by means of needle aspiration.