Non-invasive, biomedical devices have the potential to provide important, quantitative data for the assessment of skin diseases and wound healing. Traditional methods either rely on qualitative visual and tactile judgments of a professional and/or data obtained using instrumentation with forms that do not readily allow intimate integration with sensitive skin near a wound site. Here we report a skin-like electronics platform that can softly and reversibly laminate perilesionally at wounds to provide highly accurate, quantitative data of relevance to the management of surgical wound healing. Clinical studies on patients using thermal sensors and actuators in fractal layouts provide precise time-dependent mapping of temperature and thermal conductivity of the skin near the wounds. Analytical and simulation results establish the fundamentals of the sensing modalities, the mechanics of the system, and strategies for optimized design. The use of this type of ‘epidermal’ electronics system in a realistic, clinical setting with human subjects establishes a set of practical procedures in disinfection, reuse, and protocols for quantitative measurement. The results have the potential to address important unmet needs in chronic wound management.

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This is a cross sectional-descriptive study which was conducted in one urban mahalla and two rural mauza of Dhaka district. Self reporting questionnaire (SRQ) was applied on 327 adult respondents and structured clinical interview for diagnosis (SCID-NP) was applied on every second SRQ positive and every fourth SRQ negative respondent. The prevalence of neurotic disorders, major depressive disorder and psychotic disorders was 7.0% (7/1000 population), 4.0% (40/1000 population) and 1.2% (12/1000 population) respectively. The prevalence of psychiatric disorder was found higher in female 13.9% than male 10.2% and in middle and lower socio-economic class. The study would be helpful in future community survey on mental health and in formulating national mental health program and facilitating their effective implementation.

Three of the 4 commonly used acellular dermal matrix materials are resistant to in vitro penetration by S. aureus and S. pyogenes and partially resistant to P. aeruginosa. Resistance to fungal pathogens is uncertain. Antimicrobial differences across matrix materials may influence their selection for particular uses, such as treatment of refractory leg ulcers or reconstruction after skin cancer excision.