Objectives: To examine the craniofacial morphologic features of children with celiac disease and to investigate the presence of specific features in this disease. Methods: Totally 100 celiac patients between the ages of 3 and 17 years who were diagnosed with celiac disease by biopsy and 100 healthy age-and sex-matched children were included in the study. Photographs of the children were taken using a SLR digital camera by one and the same person at a natural head position. The parameters specified on the photograph were measured with ImageJ 1.50b software. Twenty eight landmarks were identified on the photos. Using these landmarks, 41 distances and 5 angles were measured. Thirty eight anthropometric ratios were calculated. Results: Twenty seven distances, 1 angle and 9 ratios were determined shorter; 3 distances, 2 angles and 7 ratios were determined larger in patients with celiac disease compared with the healthy individuals. These differences were statistically significant. Conclusions: There were significant alterations in some craniofacial morphometric parameters in children with celiac disease when compared with healthy controls. However, since the data is limited, a clear conclusion could not be achieved about a morphological feature directly associated with celiac disease in children. Further prospective studies with longer follow-up periods are warranted to determine the effects of celiac disease on craniofacial morphological measurements.

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Şan ES, Erdoğan S, Boşnak M, Şan M. Hypophosphatemia associated risk factors in pediatric intensive care patients. Turk J Pediatr 2017; 59: 35-41. The aim of this work is to determine the prevalence and risk factors of hypophosphatemia in pediatric patients admitted to intensive care unit. The study was performed prospectively in patients admitted to the Pediatric Intensive Care Unit between June 2014 and December 2014. Fifty-seven patients were included in the study. The mean age of the study population was 24 months (2-192 months); 25 patients (43.9%) were male and 32 were female (56.1%). The mean body weight z-score was -1.47 ± 2.23, and 23 (40.4%) patients had malnutrition. On admission 16 (28.1%) patients had hypophosphatemia. There were no statistically significant differences between the hypophosphatemic patient group and normophosphatemic patient groups in terms of demographic and clinical characteristics. There were also no significant differences between the two groups in terms of risk factors. Potassium and creatinine levels were significantly lower in the hypophosphatemic group, compared to the normophosphatemic group. According to a multivariate logistic regression analysis, risk factors for hypophosphatemia were low potassium level (OR: 16.76; 95% CI: 2.09 - 134.72; p: 0.008), malignant solid tumors (OR: 52.40; 95% CI: 2.04 - 1,344.32; p: 0.017, p: 0.036). and female gender (OR: 6.18; 95% CI: 1.12 - 34.00; p: 0.036). Prospective studies with larger sample size should be conducted to study the prevalence and risk factors of hypophosphatemia at pediatric intensive care unit.

ÖZET Yenidoğan döneminde bazı metabolik hastalıklar hayatı tehdit eden ensefalopati tablosu olarak ortaya çıkar. Bu durum bazı metabolizma ara ürünlerinin beyinde birikerek toksik etkiler göstermesi ile ilişkilidir. Bebekler doğumda genelde asemptomatiktir. Yaşamın ilk günlerinde toksik metabolitlerin birikimi ile hastalarda yaygın hipotoni veya hipertoni, konvülzyonlar ve letarji gibi ensefalopati bulguları ortaya çıkar. Bu yazıda emmede azalma, yaygın hipotoni, miyoklonik nöbet ve hıçkırık nedeni ile gelen ve non-ketotik hiperglisinemi tanısı koyduğumuz bir infant sunulmuştur. ABSTRACT On the newborn period some metabolic diseases may cause encephalopathy clinic which can threat the life. This is related with tke accumulation of metabolic intermediates ond the brain and their toxic effects.Babies are usually asymptomatic at birth. By the accumulation of toxic metabolytes patients have the encephalopathy symptoms such as hypotonia, hypertonia, convulsions and lethargy. In this article we report a patient who came to the clinic with decreased absorbtion, widely hypotonia, myoclonic seizures and hiccups and who has been diagnosed as non ketotic hyperglycinemia.

ÖZET:İntramusküler enjeksiyon sonrası Escherichia coli'nin neden olduğu uyluk apsesi ve yaygın pannikülit: Olgu sunumu Parenteral ilaç uygulamaları tüm tıbbi disiplinlerde rutin olarak yapılan bir işlemdir. İntramusküler, intravenöz, intraartriküler uygulamalar ve infüzyonlar apse, eklem enfeksiyonu gibi lokal komplikasyonlara yol açabilmektedir. Bu tip lokal komplikasyonlar mortalitesi ve morbiditesi oldukça yüksek bakteriyemi, sepsis ve çoklu organ yetmezliği gibi ciddi komplikasyonlara yol açabilir. Biz bu yazıda intramusküler enjeksiyon sonrası Escherichia coli'nin neden olduğu uyluk apsesi gelişen ve yaygın panniküliti olan bir hastayı sunuyoruz. Anahtar kelimeler: İntramusküler enjeksiyon, enfeksiyon, Escherichia coli, çocuk ABSTRACT:Thigh absces and wide paniculitis caused by Escherichia coli after intramuscular injections: case reportThe parenteral drug application is a routinely used method in all medical disciplines. Intramuscular, intraarticular, intravenous injections and infusions can cause local complications such as abscesses and articular infections. These local complications can lead to bacteraemia, sepsis and may lead to multiple organ failure associated with high morbidity and mortality. We present a patient with thigh abscess and wide paniculitis caused by Escherichia coli after intramuscular injections. GİRİŞParenteral ilaç uygulamaları tüm tıbbi disiplinlerde rutin olarak yapılan bir işlemdir. İntramusküler (İM), intravenöz (İV), intraartriküler uygulamalar ve infüz-yonlar apse, eklem enfeksiyonu gibi lokal enfeksiyöz komplikasyonlar ortaya çıkarabilmektedir (1-3). Biz intramusküler metamizol sodyum enjeksiyonu sonrası Escherichia coli'nin neden olduğu uyluk apsesi ve yaygın pannikülit gelişen bir hastayı sunuyoruz. OLGUDokuz aylık kız hastaya iki gündür devam eden ateş şikayeti ile gittikleri merkezde sağ uyluk anterolateral kısmına metamizol sodyum (Novalgin) enjeksiyonu yapıldığı, enjeksiyon sonrasında hastanın huzursuzluğu ve ağlama nöbetlerinin başladığı, ateşi düşmeyen hastanın enjeksiyondan bir gün sonra sağ uyluk orta kısmında kızarıklık ve morarma başladığı, ikinci kez hastaneye başvuran hastanın diğer uyluğundan enjeksiyon yapılarak taburcu edildiği, ancak hastanın huzursuzluğunun artması ve ateşinin düş-memesi üzerine hastaneye yatışının yapıldığı öğre-nildi. Bu hastanede seftriakson ve amikasin tedavilerinin başlandığı, üç günlük tedavinin ardından hastanın lezyonlarında ilerleme olması, trombositopeni gelişmesi, protrombin zamanı (PT) ve parsiyel tromboplastin zamanı (PTT) değerlerinde uzama olması üzerine hastanın hastanemiz yoğun bakım ünitesine