This letter reports an efficient phase analysis-based direct time domain resampling scheme for swept source-based optical coherence tomography (SS-OCT) systems. The unwrapped phase values, representing non-linear frequency sweeping of the laser, are extracted from the calibration signal generated by a Mach-Zehnder interferometer. Equidistant wavenumber spaces are calculated by normalizing obtained phase values followed by scaling to the maximum number of sampling points. The non-uniform fractional time index values corresponding to the uniformly distributed phase values are computed directly from the linearizer coordinates in order to eliminate the use of the polynomial fitting approach that is used in existing phase-based time domain resampling methods. This proposed linearization scheme shows a significant improvement in performance in terms of accuracy and speed in comparison with the major existing schemes. The robustness of the algorithm, as well as its impact on the resolution and sensitivity, are illustrated using an in-house-developed SS-OCT system and by performing imaging of a human finger nail and an eye model as test samples.

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Narrow bandwidth, high brightness, and spectral tunability are the unique properties of lasers that make them extremely desirable for fluorescence imaging applications. However, due to the high spatial coherence, conventional...

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