This study was conducted to investigate the effect of Marlubium vulgare plant on albino mice experimentally infected with Trichomonas muris parasite and compared it with Metronidazole drug. The oral administration method was used to estimate the effect of the plant extract. where each group of mice was administered a different concentration of the plant alcoholic extract (500, 1500, 2500, 3500) mg/kg, and 30 mg/kg of metronidazole drug was administered to another group, while the control group was administered an equal amount of normal saline solution. The results showed a significant effect of the concentrations of alcoholic extract and the drug metronidazole in the treatment of infected albino mice and showed a high treatment efficiency of 100% with a variation in the time required for complete treatment and complete elimination of parasites. The highest concentration of 3500 mg/kg resulted in complete recovery in the affected albino mice on the fourth day after treatment, while the use of the drug led to a complete recovery on the fifth day after treatment, while the infection in the control group continued to the fifth day and then died. The conclusion of this study confirmed the high therapeutic efficacy of different concentrations of alcoholic extract of M. vulgare plant in treating T. muris parasite in mice experimentally infected with it, which is comparable to the effectiveness of Metronidazole drug.

The current study was conducted to find out the prevalence of Microfilaria in cows in the western regions of Iraq, by examining 382 cows of both sexes and for ages from 1-11 years during the year 2020. The parasite was diagnosed by examining the skin scraping collected from the infected animals in the laboratory, and the results showed that the cows were infected with the microfilariae parasite by 34%, and the highest infection rate was recorded in Al-Qa’im area 51.6% and Haditha 49.%. Significant differences were observed between males (21.9%) and females (44.6%). The highest incidence rate was recorded in cows aged 3-5 years, at 45.3%, with significant differences from the rest of the ages. Furthermore, the highest incidence rate was observed in Summer seasons, reaching 64.8%. The current study concludes that cattle in the western regions of Iraq are infected with the microfilariae parasite at a high rate, and this necessitates the establishment of an integrated control approach to control parasitic diseases and prevent their spread in farm animals because they cause serious disease effects and heavy economic losses.