The application of statins in cardiology aimed at reduction of the risk of cardiovascular problems has noticeably increased over the last years. In this regard, it has been assumed that statins can be effective in the primary and secondary prevention of cerebral infarction and transient ischemic attack. The recent studies have provided contradictory data on the issue, which reduces the assignability of this group of drugs by neurologists. This review covers the characteristic features of statins in angioneurology.

Objective : to determine special features of the immunological status as a result of immunophenotyping of peripheral blood leukocytes in patients with different transient disturbances of cerebral blood circulation in comparison with patients with stroke. Material and methods . We examined 14 patients with transient ischemic attack (TIA), 7 patients with cerebral hypertensive crisis (CHC), 9 patients with lacunar stroke, and 9 volunteers. All the patients underwent immunophenotyping of peripheral blood leukocytes and their immunoglobulin level was determined by immunoturbodimetrical method on the first day after admission. Results . We have defined the specific features of the inflammatory process presented by activation of the classical way of inflammation in CHC patients on the first day of the illness in the form of increased level of proteins of the complement system, activity of T- and B-cellular links of immunity in a combination with low expression of adhesion molecules. We have revealed depression of T-cellular immunity without activation of B-cellular immunity in TIA group, which distinguishes transient disturbances of cerebral blood circulation from stroke. Conclusion. Absence of the activation of B-cellular immunity in patients with CHC and TIA and low level of the expression of adhesion molecules make the sanogenic potential of transient disturbances of cerebral blood circulation in comparison with stroke.

The article presents up-to-date information on the structure of C-reactive protein, its functions and role in risk stratification of cardiovascular diseases, cancer and mental disorders.

Objective. To evaluate the effectiveness of extremely high frequency (EHF) millimeter range electromagnetic radiation (EMR) of low intensity in patients with malignant neoplasms suffering from chronic pain syndrome (CPS).Materials and methods. The study included 60 patients with diagnosed malignant neoplasm (MN) who were treated in a palliative care unit. They were divided into 2 groups. The main group consisted of 30 patients who underwent additional EHF-exposure with a course of 10 sessions of 15 minutes simultaneously with the main therapeutic measures. The comparison group consisted of patients who did not undergo electromagnetic exposure 30 people. Questioning was conducted twice: on the 2nd and 14th days of treatment. Treatment efficiency was assessed using standardized questionnaires.Results. The analgesic effect of additional use of EHF therapy with a fixed frequency of 53.534 ± 0.015 GHz in patients with MN was significantly higher than the analgesic effect of standard treatment. In particular, there was an increase in mobility, as well as a decrease in depression and reactive anxiety.Conclusion. The additional use of EHF therapy in patients with MN provides the advantage of improving quality of life by reducing CPS, improving psychological well-being and improving the ability to move independently.

No abstract