Highlights Shrimp wastewater is a rich source of P- and N-compounds suitable for cyanobacterial growth. Phosphate in shrimp wastewater can be efficiently removed by Synechocystis ΔSphU. ΔSphU accumulates high PHB with commercial value when shrimp wastewater contains low nitrate level. Shrimp wastewater can be used for biodegradable plastic production by cyanobacterial cell.

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