Background: Chronic Obstructive Pulmonary Disease (COPD) is a common, preventable and treatable disease that is characterized by persistent respiratory symptoms and airflow limitation that is due to airway and/or alveolar abnormalities usually caused by significant exposure to noxious particles or gases. HT and DM have been recognized to coexist with COPD. Several risk factors have been associated with HT and DM in people with COPD: Smoking, systemic inflammation, obesity and physical inactivity. Objective: To estimate Prevalence of diabetes and hypertension in Chronic Obstructive Pulmonary Diseases amongst study participants. Material and Method: The Cross-sectional study was conducted on 161 diagnosed COPD patients from August 2017 to December 2019 in Department of Respiratory Medicine Medical College and Tertiary Health Care Institute Nashik was included. Written informed consent was taken from all study participants and those who gave consent were enrolled in the present study. Result: Out of 161 COPD patients, prevalence of hypertension was 45.96% while prevalence of DM was 22.36%. The Highest prevalence of DM in Female (33.33%), HTN in Male (48%) and both DM and HTN in Female (8.33%), active smokers were mostly associated with DM and/or HTN. In stage IV (71), DM, HTN and both DM and HTN were recorded in maximum no. of cases, whereas in patients of Stage I - COPD least level were found. Increase association of DM and/or HTN increases with severity of obstruction. Conclusion: Prevalence of HTN was recorded more than DM. DM and HTN were found to be more prevalence in severe and very severe COPD patients. The COPD patients should be screened for DM and HTN at the time of diagnosis to prevent DM and/or HTN related complications in COPD patients.

Background: Our knowledge on reasons of non-acceptance and complication to H1N1 Vaccination by health care workers is limited. A better understanding of factors having significance in vaccine acceptance is crucial. With this background in mind present study was conducted at tertiary care centre to determine the Acceptance, Compliance, and Complication of anti-H1N1 seasonal vaccine among Health Care Workers (HWCs). Materials and Methods: Prospective Observational study was conducted to observe the rate of acceptance, compliance and complications of anti H1N1 seasonal vaccine among 100 health care workers in the period of December 2015 to December 2017 in Tertiary Health Care Centre. All participants were counselled 3 times at interval 6 months (0, 6, and 12 months) regarding H1N1 vaccine. Result: Vaccine acceptance rate among health care workers was only 03% before counseling. The main cause for not acceptance of vaccination was fear of adverse effects reported by 27% health care workers followed by cost of vaccine (12%) and work pressure (10%) or nonavailability of time. Conclusion: As counseling sessions progressed health care workers also started accepting vaccination. After completion of third counseling session rate of vaccine acceptance increased from 3% to 71% and also negative and doubtful conception of health care workers were and changed completely. After counseling their knowledge regarding influenza vaccine was increased. Even though some post vaccination complications had been reported by recipient; those symptoms lasted for short duration of time and there was no serious adverse effect of H1N1 vaccine.