Objective. To develop a questionnaire as a screening tool for adverse reactions to foods in children and to assess the technical reproducibility by test-retest. Methods. Reproducibility of the questionnaire was performed by the literature review, preparing the preliminary questionnaire, peer review, pretest, and retest analysis. The study of the test-retest reproducibility was cross-sectional and descriptive. Kappa coefficient was used to study the reproducibility of the questionnaire. The sample consisted of 125 2–4 year-old children from 15 daycare centers in Recife, Brazil, and interviews with parents or caregivers were used to collect data. Results. From the total children, sixty-three were boys (50.4%), forty-six were two years old (36.8%), forty-seven were three years old (37.6%), and thirty-two were four years old (25.6%). Forty caregivers reported that their child had health problems with food. Most frequently reported offending foods were milk, peanuts, shrimp, and chocolate. Nine questions showed a good Kappa index (≥0,6). Conclusions. The questionnaire used needs to be resized and reshaped on the basis of the issues with good internal consistency and reproducibility. The use of a validated and reproducible questionnaire in the children represents an important contribution towards assessing an eventual rise in overt food allergy.
ResumoAlergias alimentares são comuns e estão se tornando um problema de saúde por gerarem um impacto negativo na qualidade de vida. Caracterizam-se por um conjunto de manifestações clínicas consequentes de mecanismos imunológicos decorrentes do contato com determinado alimento. O presente estudo teve por objetivo apresentar uma revisão sobre a alergia alimentar e apontar os exames laboratoriais utilizados no diagnóstico. Esta revisão bibliográfica contou com 46 publicações entre 1990 a 2012, obtidos das bases Medline, Lilacs e SciELO, e sites sobre alergia, utilizando-se os descritores alergia alimentar, diagnóstico, e alimentos. Os alimentos mais citados como causadores de alergia são: leite, ovo, amendoim, castanhas, frutos do mar e soja, sendo os principais alérgenos de natureza proteica. Para evitar a alergia alimentar, a mucosa intestinal precisa estar íntegra. As reações podem ser IgE-mediadas, não-IgE-mediadas ou mistas. Quanto aos métodos diagnóstico, eles podem ser in vivo com o teste cutâneo e os de provocação oral, ou in vitro, os quais medem a IgE sérica específica, a IgG, ou os basófilos ativados no sangue. A alergia alimentar é um problema não resolvido devido ao incompleto conhecimento sobre sua patogênese. Necessita de anamnese adequada onde os mecanismos imunológicos e os alimentos envolvidos serão apresentados. O padrão de referência atual para o diagnóstico é o teste de provocação oral duplo-cego controlado por placebo. Apesar de mais dispendiosos, os exames laboratoriais vêm se mostrando uma alternativa eficaz no diagnóstico de alergia alimentar. Porém, mais incentivo ainda se faz necessário. AbstractFood allergies are common and have become a health problem by generating a negative impact on quality of life. They are characterized by a series of clinical reactions caused by immunologic mechanisms resultant of contact with a specific type of food. This research had as an objective to present an review of food allergy and indicate the laboratory diagnostic methods available. This literature review was developed by 46 publications between 1990 and 2012, obtained by the data bases: Medline, Lilacs and Scielo, and from web sites about food allergy, taking into consideration the key-words food allergy, diagnosis and food products. The main food products mentioned as the major allergy trigger are: milk, egg, peanuts, chestnuts, sea food and soy; and major food allergens are identified as proteinaceous nature. In order to avoid the food allergy, the intestinal mucosa must be intact. The reactions may be IgE-mediated, non-IgEmediated or mixed. Regarding the diagnosis, they can be in vivo with the Prick Test and Food Challenges. They can also be as in vitro, which measures the specific seric IgE, the IgG, or the activated basophil on blood. Food allergy is a non-solved problem due to the lack of knowledge about its pathogens. It needs an appropriate anamnesis, which the immunologic mechanisms and the food products involved will be primarily presented. Nowadays, the gold standard of specific food alle...
Resumo: Atividades de saúde primária e básica normalmente são realizadas por profissionais que possuem conhecimento generalizado, e o serviço oferecido neste contexto é essencialmente descentralizado. Mesmo com a inserção de tecnologias em saúde, bem como a aceitação do uso de equipamentos móveis, percebe-se que ainda há uma lacuna quanto ao uso desses meios em saúde básica, além de se fazerem necessárias ferramentas de apoio à tomada de decisão baseada nas evidências coletadas. Nesse contexto, este artigo apresenta uma proposta e a experiência de construção de sistema de suporte à decisão móvel de apoio ao diagnóstico médico utilizando árvores de decisão. Palavras-chave:
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.