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This paper proposes an E-cosmetic function for digital images based on physics and physiologically-based image processing. A practical skin color and texture analysis/synthesis technique is introduced for this E-cosmetic function. Shading on the face is removed by a simple color vector analysis in the optical density domain as an inverse lighting technique. The image without shading is analyzed by a previously introduced technique that extracts hemoglobin and melanin components by independent component analysis. Experimental results using UV-B irradiation and the application of methyl nicotinate on the arms support the physiological validity of the analysis and the effectiveness of the proposed shading removal. We synthesized the way facial images changed due to tanning or alcohol consumption, and compared the synthesized images with images of actual changes in skin color. The comparison shows an excellent match between the synthesized and actual images of changes due to tanning and alcohol consumption. We also proposed a technique to synthesize the change of texture in pigment due to aging or the application of cosmetics. The pyramid-based texture analysis/synthesis technique was used for the spatial processing of texture. Using the proposed technique, we could realistically change the skin color and texture of a 50 year-old woman to that of a 20 year-old woman.

Extracts of Micromelum integerrimum (Buch.-Ham. ex Coleb.) M. Roem. were fractionated based on in vivo activity in mice in the P-388 lymphocytic leukemia system. Activity in ethanol extracts was concentrated in the chloroform partition fraction, which was further resolved by chromatography on silica gel. The known coumarins, micromelin and scopoletin, were crystallized from the active fractions and demonstrated to have antitumor activities. Micromelin was converted to the corresponding butenolide (deoxymicromelin) which was inactive in the 9KB assay.

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Abstract. We have developed a simple and effective method for everyday measurement of translucency with a handy spectral reflectometer using edge loss. Edge loss can be used to quantify the translucency index in terms of changes in reflectance under two types of measurement conditions. Here, a measurement condition represents the pairing of an illumination area and a measurement area. As a measure of the degree of lateral spread of reflected light, the translucency index can influence the appearance of human skin because this index represents eventual translucency. First, we estimated how edge loss changes when measurement conditions are varied. We then selected the combination of two measurement conditions of large and small edge loss to minimize errors. Finally, we estimated actual skin translucency changes before and after treatments comprising acetone-ether immersion and ultraviolet irradiation. The results were qualitatively consistent with the expectations under variations in absorbance and scattering capacity, indicating the effectiveness of this method in evaluating translucency. This method allows simultaneous measurement of translucency and reflectance as a spectrum, and also appears applicable for daily use, although common optical parameters cannot be derived using this method alone.