mortalidad. Resultados: Se incluyeron 154 casos, 59 mujeres y 95 hombres. El principal órgano causante de sepsis abdominal fue el apéndice (41.6%). La mortalidad global fue del 14.3%. La presencia de fallas orgánicas fue del 35.1%. El valor medio de HDL se situó en 37.64 mg/dl (desviación estándar: ± 16.16). Los hallazgos, sometidos a verificación estadística mediante la prueba t de Student, mostraron significancia entre los casos con SOFA > 4 (p = 0.01) y Mannheim > 26 (p = 0.001), CONUT > 6 (p = 0.001), presencia de fallas orgánicas (p = 0.001) y mortalidad (p = 0.003). Conclusión: Los valores de HDL se relacionan con la gravedad, con el desarrollo de fallas orgánicas y con la mortalidad en la sepsis.

Background: Biomarker combinations can improve timely diagnosis and survival. Objective: To determine the usefulness of serum procalcitonin concentration (PCT), C-reactive protein (PCR) and the PCR/PCT index as predictors of mortality.Method: Retrospective study of patients diagnosed with abdominal sepsis during the period from April 2017 to February 2018. Results: We included 182 cases. In the survivors, the mean PCR was 170 and procalcitonin (PCT) 10.5. In the deceased, the mean of C-reactive protein (CRP) was 328 and that of PCT was 17.6. When applying the student's t-test for independent samples, it was found that these differences were significant for PCR (p = 0.001); however, for PCT it was not significant (p = 0.460). Afterwards, the PCR/PCT index was studied, as a predictor of mortality, in the deceased cases a PCR/PCT score of 7534 (standard deviation [SD]: 19,303) and for survivors of 538 (SD:805) (p = 0.001) was obtained. Conclusion: CRP is associated with mortality, serum PCT does not correlate with mortality. The PCR/PCT index seems to be a better indicator to predict mortality in patients with abdominal sepsis due to secondary peritonitis.

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Background: Abdominal sepsis represents the host's peritoneal inflammatory response to microbial invasion, which may be mild or severe, depending on the degree of contamination of the peritoneal cavity; with a reported mortality of 17%. The Mannheim peritonitis index is a clinical tool and a predictor of mortality in patients with peritonitis, with high sensitivity and specificity. Objective: To determine if there is a correlation between the score obtained by the Mannheim peritonitis index, and mortality, in patients with abdominal sepsis. Method: A retrospective, observational, cross-sectional study, during the period between July 2013 and January 2014, in patients diagnosed with abdominal sepsis, attended at the General Hospital of Mexico Dr. Eduardo Liceaga. Results: We included 177 cases, 85 of the female sex and 92 of the male sex. The average age was 43 years. The most common organ responsible for abdominal sepsis was the appendix. Mortality of 18 cases (10.2%). The cases were divided, according to the Mannheim index, in mild cases (< 25 points) and severe case (> 26 points). Of 27 severe cases, 8 (29.6%) died, while of the 150 mild cases 10 (6.7%) died (odds ratio: 5.895; 95% confidence interval: 2.071-16.77; p < 0.05). Conclusions: The Mannheim scale is a good predictor of mortality for patients with abdominal sepsis. The optimal cut-off point is 20.

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