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college of medical laboratory science. 2. Sudan university of science and Technology, colleges of medical laboratory science.(Head department of clinical chemistry). 3. Sudan university of science and Technology, colleges of medical laboratory science.

Alcoholism is a major issue globally. It is estimated to be the fifth leading risk factor for global disability-adjusted life years. Commonly chronic alcoholic patients develop a variety of acid base and electrolyte disturbances, which play a significant role in their morbidity and mortality. Physicians should recognize these abnormalities and the underlying interrelated patho-physiological mechanisms for their prompt diagnosis and appropriate management. This study was carried out to measure serum levels of the magnesium and Phosphorus in Sudanese alcoholism. A total of one hundred and twenty subjects were enrolled in this study, divided into two groups sixty alcoholism and sixty normal individual serve as control were collected from period between May to June 2017, chosen randomly from Khartoum state , to assess the blood levels of magnesium and phosphorus. Serum magnesium and Phosphorus were measured by using full automated chemical analyzer BS 380 and results were analyzed using statistical of package social science (SPSS), computer program. The study showed that, alcoholism had significantly decreased the means of serum magnesium and phosphorus (3..91±0.39mg/dl) vs. (5.34±0.68 mg/dL) P<0.05, (2.48±0.71 mg/dl) vs (4.32±0.66 mg/dl) p value <0.05 respectively . There were significantly weak negative correlation between serum magnesium, phosphorus levels and duration of alcoholism (r=-0.264 , p value=0.041), (r = − 0.034 , P, value = 0.008 ) respectively and there was insignificant weak positive correlation between serum magnesium in alcoholism and age (r = 0.214 and P, value= 0.089 ) while there was insignificant weak negative correlation between serum phosphorus in alcoholism and age (r = − 0.097 and P = 0.460). The study concluded that, the level of magnesium and phosphorus were significantly decreased in alcoholism.

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Total proteins, albumin, cholesterol, triglyceride and tuberculosis. Background: Tuberculosis or TB is a common and often deadly infectious disease caused by various strains of mycobacterium; usually Mycobacterium tuberculosis in humans. Objectives: The aim of this study to evaluate the level of serum albumin, total proteins, cholesterol and triglyceride among Sudanese patients with Tuberculosis. Methods: Cross sectional study was conducted during the period from March to May 2017, eighty samples from known patients with TB as case and forty samples from healthy person as control. The level of total proteins, albumin, cholesterol and TG was measured using Mindray BS-120; Data were collected using structural questionnaire. Data analysis was carried out by means of statistical package for social science (SPSS version 16). Results: The mean levels of total proteins, albumin, cholesterol and triglyceride showed significant decreased in tuberculosis patients when compared with healthy individuals with (P. value = 0.000, 0.000, 0.015 and 0.000) respectively. There were insignificant different in the levels of total proteins, albumin, cholesterol and TG in tuberculosis patients according to gender. The result of this study showed that, there was significantly decreased in BMI in patients with tuberculoses compared to control group (p-value =0.000). There were negative correlation between the levels of serum total proteins, albumin, total cholesterol , triglyceride and ages.(r=-0.356, p, value=0.001) (r=-0.273,p, value=0.014)(r=-0.296,p , value=0.008)(r=-0.223, p , value=0.047) respectively. Conclusion: The levels of total proteins, albumin, cholesterol and triglyceride were significantly decreased in Tuberculosis patients.