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The animal model response against genetically modified product may provide food safety information. This study was performed to observe behavior, histopathology and physiological responses of Wistar rat fed on the diet containing growth hormone (GH) transgenic common carp (Cyprinus carpio) meal (Ccm). Thirty rats of three-month-old (BW: 115.67–139.50g) were divided into five treatments (six rats per treatment). The treatments were rats fed on the commercial diet without Ccm (control), a re-pelleted diet containing 15% (NT-15) and 45% non-transgenic Ccm (NT-45), a re-pelleted diet containing 15% (TG-15) and 45% GH transgenic Ccm (TG-45). Rats were kept for three weeks, fed twice a day according to treatment by 30 g/day/rat and water was provided ad-libitum. Rat behavior was observed every day during feeding. Serum glutamic oxaloacetic transaminase (SGOT), serum glutamic pyvuric transaminase (SGPT), urea, and creatinine were measured at initial and the end of the experiment. Histology observation was made for liver, kidney, and brain tissues. Our results showed that behavior, histopathology, SGOT, SGPT, urea and creatinine levels of rat fed with control, NT- and TG-Ccm diets were similar. All rats survived until the end of the experiment. Thus, within the dose level of this study, GH transgenic Ccm showed no toxicity or effect on behavior and physiology of Wistar rats.

No abstract

In order to lower the fish mortality during transportation, the chopped banana stem (BS) was added during the African catfish transport procedure. The fish were packed in plastic bags with a density of 100 fish in 1.5 L water. The chopped BS was added into the plastic bags with different concentrations: 0 (control), 5, 10, and 15 mg L−1. The fish were transported for 5 hours. After transportation, the fish, together with the added chopped BS, were distributed into glass tanks and acclimated for 24 h. After 24 h, the results showed that the BS treatments had lower cumulative mortality compared to the control with the lowest mortality was observed at the 15 mg L−1 concentration (p<0.05). The BS treatments also increased the antioxidant defence and the immune status of the fish thus might be responsible for the reduced mortality.