Friction is an ever-present obstacle that causes energy loss in mechanical parts. To alleviate this nuisance, we carried out experimental studies on a brand new additive called Polytron to assess its role in the minimization of friction and wear. The wear, the volume wear rate, the wear coefficient, and the coefficient of friction of the aluminum surface were measured at room temperature with pin-on-disk tribometer without and with 10% Polytron in Helix oil. In the base oil Helix, their values were found to be 70 μm, 1.28 × 10 −3 mm 3 / min , 1.27 × 10 −10 m 2 / N , and 0.012, respectively, which with the incorporation of Polytron additive in the Helix oil correspondingly reduced to 20μm , 6.08 × 10 −5 mm 3 / min , 4.22 × 10 −11 m 2 ___ N , and 0.004. The experimental verdict points to an ionic character of the additive in that it impregnates the crystal structure of the metal, thereby prompting a hard surface layer which subsequently curtails wear and friction.

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BACKGROUND: Hair is a dead tissue and is composed of keratin and related proteins. Hair is a protein offew growing cells at the base of the hair root. If the patient is diabetic glycosylation occurs in these growingcells.Since the extent of glycation of hair protein varies with the distance from the hair root, we hypothesizedthat glycation of hair protein might provide insight into blood glucose level over a period of several mouthsto one year.So hemoglobin Ale (HbAIc) may be established as an indicator of long-term blood glucosecontrol in diabetic patients. It is formed by non-enzymatic reaction of glucose with Hb.The objective of thisstudy was to estimate the furosine(an intermediate in the breaking down of amadori compounds likeglycosylated proteins) level by HPLC of glycosylated hair proteins, to find interrelation of fasting glucosewith HbAIc and furosine in diabetic patients, to determine the efficacy of Glycosylation of HbA,c andfurosinemay be a reliable marker in diabetic patients.STUDY DESIGN: This study was carried out in the department of Biochemistry Basic Medical SciencesInstitute (BMSI) Jinnah Postgraduate Medical Centre Karachi.METHODS: A total of 200 subjects were included in the study. 100 diagnosed type II and 100 controlnormal subjects. Hair from the scalp 12 cm long and 50 mg in weight was collected from each subject tomeasure furosine level. Furosine level was determined by HPLC and HbAIc, FBSand serumprotein byenzymatic kit method.RESULTS: When the mean values were compared with that of control it depicted significantly high level(0.001) of furosine, HbAIc and FBS.CONCLUSION: The furosine, HbAIc and FBS levels increases in diabetic patients while total serumprotein were unaffected. Weight and BMI increases in diabetic but height was unaffected.KEYWORDS: Diabetes mellitus type II, furosine, HbAIc, fasting blood sugar, glycation ofhair protein

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