We studied the three-dimensional structure and patterns of distribution of the lingual papillae of healthy rats (the norm) and their changes in the process of development of diabetes mellitus І type. The research was conducted on 65 laboratory rats of the Weestar line. The research investigated the mucus shell and the microcirculatory network of the tongue. The distribution and three-dimensional structure of the papillae of the tongue were studied using a scanning electron microscope. It was found that there are 5 morphological subspecies of filiform papillae on the dorsal surface of body of the tongue: true filifom, flattened, thin and giant conical and brush-like. Isolated fungiform papillaе are unevenly distributed between filiform papillaе. The dorso-lateral edge of the dorsal lingual surface is covered by foliate papillae. The unique oval papilla vallate is located in the back-end of the middle line of the root of the tongue. The far back of the root of the tongue lacks papillae, is flattened and covered by squamous formations. The distribution and types of lingual papillae is similar in rats to other rodents. In the process of development of diabetic glossitis a reduction in the height of different types of papillae of the tongue was observed, and an increase in the amount of keratinized mass, which plays a role in the fixation of microflora on the surface of the mucus shell, which as a result may lead to development of inflammatory process in the tongues of rats with experimental diabetes mellitus. The stages of morphological and morphometric changes in the mucus shell and microcirculatory network of the tongues of rats with diabetes mellitus were investigated, the characteristic signs of these changes were marked. On the basis of morpho-functional changes of the tongues of rats with experimental streptozotocin induced diabetes mellitus, two stages of development of pathomorphological changes were distinguished: 1) reactive changes (2–4th week) and 2) destructive processes (6–8th week). At the end of the first stage there was a reduction in height of the filiform papillae and width of mushroom-like papillae in the mucus shell of the tongue, an increase in its keratinization, a considerable reduction in the number of cells in the deeper layers of the epithelium of the tongue and the adsorption capacity of superficial epіtheliocites diminished, a significant reduction in the diameter of path clearance of all departments of the microcirculatory network is traced here. At the end of the secondary stage, there was a reduction in the sizes of all papillae of the back of the tongue, in all links of the microcirculatory network there was a development of diabetic microangiopathy which is characterized: by narrowing of the arterial and exchange links on a background expansion of capacity link. The question of influencing the pathological process in the vessels of the microcirculatory network on the state of the mucus shell of the tongue in animals with experimental streptozotocin induced diabetes mellitus is discussed.

Purpose: to study indicators of general and special physical condition on different stages of macro-cycle training. Material: in testing qualified boxers-28 sportsmen-participated. Characteristics of general and special fitness were registered. Results: it was found that structure of general and special physical qualities can be described by 9 factors, explaining about 80% of total sample variance. It was also determined that factorial structure of general and special physical fitness indicators does not change depending on stages of trainings. At every of the tested stages the marked out factors do not depend on each other. These factors are separate necessary sides of training. It was found that on general preparation stage of training these factors characterize sides of fitness: effectiveness of punches of strong and weak arms; special speed and power endurance; general endurance and strength of muscles (hands' flexors); specific sensor-motor reaction; condition of upper girdle muscles; general speed and power endurance; speed of punch movement. Conclusions: when distributing training means and loads it is necessary to uniformly doze correlation of means for all marked out factors. It ensures growth of boxers' spots results. Information about the authors: Gaskov A.V.; http://orcid.org/0000-0003-3076-5429; gaskov@bsu.ru; Buryat state University; Smolina st., 24a, Ulan-Ude, 670000, Russia. Kudryavtsev M.D.; http://orcid.org/0000-0002-4377-0879; kumid@yandex.ru; Siberian Federal University; Siberian State Aerospace University; 79 Svobodny pr., Krasnoyarsk, 660041, Russia. Iermakov S.S.; http://orcid.org/0000-0002

Baskevich, O. V. (2017). Condition of erythrocyte membranes in people with mental and behavioural disorders caused by alcohol consumption.We studied the morphological features of the restructuring and osmotic stability of erythrocytes of 30 people with mental disorders and disorders of behavioral reactions caused by 5-7 years consumption of alcohol, the objects of the research being in a state of abstinence during the period of the investigation,. The study of quantitative composition of red blood cells and hemoglobin, as well as their ratio in people with mental and behavioural disorders developed as a result of alcohol consumption showed a decrease in the number of red blood cells and hemoglobin of 42.2% and 25.1%, respectively, indicating the presence in those people of anemic hypoxia. This is closely correlated with a decrease of osmotic resistance of red blood cells to different concentrations of sodium chloride solutions, whereby the state of erythrocyte membranes deteriorates and their resistance to hemolysis decreases. Parallel to this, is a reduction in the size of red blood cells coupled with a variety of changes in their microrelief. Conformational changes of erythrocytes are closely correlated with changes in the activity of enzymes responsible for the biotransformation of xenobiotics, primarily products of lipid peroxidation. It is shown that activity of the erythrocyte antioxidant defense system is sharply reduced as a result of increase in partially oxidized products of metabolism. It was found that the state of red blood cells is a sensitive indicator of the normal course of physiological changes, biochemical and biophysical processes in the bodies of people with mental disorders and behavior reactions developed due to consumption of alcohol.At the same time, the measurement of the osmotic resistance of red blood cells and changes in the shape of red blood cells connected with this phenomenon is an important research method for studying mechanisms of pathological processes and the action of certain drugs or biologically active substances, expands the possibilities of establishing the depth of destruction of body tissues, and also provides excellent opportunities for researchers to identify the effectiveness of treatment and prevention for people with mental disorders and behavior reactions caused by consumption of alcohol. This article discusses prospects of studies of the level of glutathione peroxidase activity in the erythrocytes among people with mental and behavioural disorders as a marker of highly specific homeostasis in the human body in response to long-term alcohol consumption, and considers using this index as a criterion for selecting patients for different groups of physical rehabilitation and recreation according to the level of rehabilitation potential. Стан мембран еритроцитів у людей із розладами психіки та поведінки внаслідок вживання алкоголю О. В. Баскевич Прикарпатський національний університет імені Василя Стефаника, Івано-Франківськ, УкраїнаУ 30 людей із розладами психіки та...

Purpose:to study types of the cardio-hemo-dynamic reaction of an organism and morpho-biochemical changes of erythrocytes of peripheral blood of female volleyball players on physical activity of the maximum aerobic power. Material:18 female volleyball players with different qualification participated in the experiment (age -22,0±0,6 years). It is investigated cardio-hemo-dynamic (by functional methods), functional changes (by biochemical methods) and structure of erythrocytes (by means of the scanning electronic microscopy) before and after maximum (3,5 W/kg of body mass) physical activity. Results:It is determined that the maximum physical activity causes essential changes in cardio-hemo-dynamic. Such changes depend on the morphological reorganization of peripheral blood erythrocytes (increase in the index of erythrocytes deformation) and closely correlate with biochemical changes (decrease of ATP concentration and increase of magnesium concentration in erythrocytes). It is discussed the possible mechanisms of realization of reaction features of the organism of female volleyball players to physical activity of the maximum aerobic power. Conclusions:the physical activity of the maximum aerobic power finds typological features of the cardio-hemo-dynamic reaction of the female volleyball players' organism. Such features are expressed by conformational changes of erythrocytes of peripheral blood. They depend on the concentration of separate macroelements in these cells and type of cardio-hemo-dynamic. Cite this article as: Mytckan BM, Verbovyi VP, Chovhan RYa, Zemska NO, Kryzаnivskaya ОF, Bublyk SА, Моcherniuk VB, Faichak RI, Pjatnichuk GO, Popel' SL, Baskevich OV. Influence of physical activity of the maximum aerobic power on hemodynamic and morpho-biochemical of change of erythrocytes of female volleyball players. Pedagogics, psychology, medicalbiological problems of physical training and sports, 2018;22(5):272-279.

Purpose: to study life style of 50-65 years' age university teachers depending on their physical functioning and its connection with behavior habits. Material: questioning of 150 respondents was fulfilled by specially prepared questionnaire. Anthropometric testing was conducted. Results: it was found that most of the questioned spend time watching TV or reading and pay very little attention to physical functioning. We also found that most of respondents deal with household chores but want to do something outdoors (practice public activity). There is a trend to avoid smoking among them. Only 5.0% are cigarette smokers. The rest have never smoked or gave up smoking more than 10 years ago. Among the partners of the questioned there are a lot of smokers (16.2%). Most of the questioned have friends and relatives, who can help to achieve the highest level of physical functioning. 18.9% of partners of the questioned regularly practice sports. Some useful for health habits are observed in life situations of all respondents. Conclusions: the received data witness about purposefulness of seeking of effective ways of pre retirement age HEE teachers' involvement in active recreational functioning. We have also found that there are time reserves for this purpose.