Rheum palmatum is a potential candidate to be explored for the treatment of hepatocellular carcinoma.

This study was prepared to explore the effect of ginger extract in defeating the Ehrlich Ascites Carcinoma (EAC) injected subcutaneously in mice and induced solid tumour. After the solid tumour formation; the mice were classified into four groups (control, tumour untreated, ginger and ginger & tumour). Eight mice were grouped separately in each cage. Mice were killed and dissected at the end of this investigation; liver and kidney were removed for histopathological study. The biochemical parameters (ALT, AST, Urea, Creatinine, MDA, SOD and CAT) were measured in the sera of all tested groups. Ginger extract ameliorated the histological structures of both liver and kidney to be near to control, modulated the elevated values of (ALT, AST, Urea, Creatinine and MDA) and reduced values of (SOD and CAT) to record slightly normal readings. Tumour volumes reduced significantly and the destructed genomic DNA retained the normal pattern. Ginger has no pathological effects on control mice.

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The present study aimed to know if the food of Spalax leucodon Egyptiacus has a role in its resistance to cancer. In vitro cytotoxic effects of the main food of Spalax leucodon Egyptiacus as a daily meal that was Asphodelus microcarpus which planted in Marsa Matroh governorate Eldabaa region .We use two fractions of the extract of this plant (Ethyl Acetate &Precipitate), cell viability and cytotoxic activities were assessed using The sulforhodamine B( SRB) assay, IC50 values were estimated for the A375 melanoma. We revealed that the IC50 for the A375 melanoma was 83 ug/ml for Ethyl Acetate (EtOAc) fraction, 65ug/ml for Precipitate (PPT) fraction after 48 hours of treatment. Asphodelus microcarpus fraction has considerable cytotoxic effects on the human melanoma cell line , its show effect on cell line A375 human melanoma ,further studies are required to emphasizes the relation between resistant cancer in Spalax leucodon Egyptiacus and its main food.

The present study aimed to evaluate the antitumor activity of newly synthesized oxidized form of sodium hypochlorite. Different cell lines were susceptible to Sodium hypochlorite cytotoxicity at acute, LD 50 and therapeutic doses of NaOCl. Therapeutic dose of sodium hypochlorite modulated the significantly reduced level of Hb, IL-12, TNF and the increased levels of creatinine, GPT and GOT towards the normal values. The histopathological study of liver, kidney and spleen groups showed a very significant improvement compared to normal and positive control groups. Sodium Hypochlorite exhibited an anticancer effect on different cell lines in vitro and against EAC in mice.