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Objective: To evaluate a novel clinico-biochemical score for screening of inherited metabolic diseases (IMDs) in children in our setup.

Objective: To determine association between Serum ferritin and C-reactive protein (CRP) in children having iron scarcity anemia. Study Design: Cross sectional study. Place and Duration of Study: Pathology Department, Combined Military Hospital Multan Pakistan, from Jun to Dec 2018 Methodology: One hundred and thirty-eight (138) children were consecutively selected as per inclusion and exclusion criteria. Each sample of blood was collected from children for serum ferritin, Blood complete picture (Blood CP) which include hemoglobin level and red blood cell indices and serum sample for C-reactive protein (CRP). Sandwich chemilumine-scence immunoassay technique was used to analyze serum ferritin, Blood CP was analyzed on sysmex and C-reactive protein was analyzed immuneturbidi-metric method. Result: A total of 138 children were included in our study. Mean age group of our population is 4.5 ± 0.65 years. Out of these 138, 67 (49%) were male children and 71 (51%) were female children. CRP was found negative in 50 (36%) and positive in 88 (64%) children. ANOVA and chi-square test showed association between CRP and anemia was statically significant. Conclusion: Increased ferritin level, secondary to inflammation may mask an underlying iron inadequacy in children. CRP in children with normal or high ferritin can be helpful in diagnosing iron deficiency. Serum ferritin was found to be positively correlated with CRP in children.

Objective: To find out association of lipid profile and body mass index (BMI) profile among cases having chronic hepatitis C virus (CHCV) infection. Study Design: Cross sectional study. Place and Duration of Study: Departments of Medicine and Pathology, Combined Military Hospital, Multan Pakistan, from Mar 2019 to Feb 2020. Methodology: A total of 320 cases of both genders, aged 18-60 years, having chronic hepatitis C virus infection were enrolled. After taking relevant history and physical examination, venous blood sample of each patient was taken and sent to institutional laboratory for analysis of serum total cholesterol (TC) level, serum triglyceride (TG) level, low density lipoprotein (LDL), high density lipoprotein (HDL) were analyzed. Body mass index among all the study participants was also calculated. Results: Out of a total of 320 cases, there were 152 (47.5%) male and 168 (52.5%) female. Mean age was 41.7 ± 8.1 years. Most of the cases, 97 (30.3%) were between 41-50 years of group. Dyslipidemia was noted in 144 (45%) cases. Increasing age and increasing Body mass index were found to have statistical significance with the presence of dyslipidemia (p-value <0.05). Conclusion: Increasing age and body mass index have significant association with dyslipidemia in patients with chronic hepatitis C virus infection. Lipid profile altered among different age and body mass index groups.