Background and Objective
Periodontitis may crosstalk with renal diseases, yet that remains unclear. We investigated whether the renal alterations caused by induced periodontitis are reversible after removal of the ligatures in experimental ligature‐induced periodontitis.
Material and methods
Twenty‐four female rats were divided into three groups: control (without periodontitis), periodontitis (20 days of ligature‐induced periodontitis), and P20‐20 (20 days of ligature‐induced periodontitis and 20 days after ligature removal). The following periodontal parameters were assessed: gingival bleeding index, probing pocket depth, myeloperoxidase activity, and alveolar bone height. For renal tissues, histopathology, malonaldehyde (MDA) levels, glutathione (GSH) content, and renal weight were evaluated. In the blood, creatinine, uric acid, albumin, total cholesterol, total protein, and glucose levels were assessed. Total protein and creatinine levels in urine were also investigated.
Results
Rat renal tissues did not demonstrate reversal of periodontitis‐related changes in the P20‐20 group in terms of MDA, GSH, and histopathological evaluations when compared to the periodontitis group. Accordingly, only total cholesterol levels were reversible in the P20‐20.
Conclusion
Renal alterations caused by ligature‐induced periodontitis persisted even after removal of ligatures in rats.
We define families of aperiodic words associated to Lorenz knots that arise naturally as syllable permutations of symbolic words corresponding to torus knots. An algorithm to construct symbolic words of satellite Lorenz knots is defined. We prove, subject to the validity of a previous conjecture, that Lorenz knots coded by some of these families of words are hyperbolic, by showing that they are neither satellites nor torus knots and making use of Thurston's theorem. Infinite families of hyperbolic Lorenz knots are generated in this way, to our knowledge, for the first time. The techniques used can be generalized to study other families of Lorenz knots.
Interacting with computers has become part of our daily lives. This interaction results in large amounts of personal information, spread throughout places and applications. As a consequence, it is quite difficult to get an overall view of all our information or to find a specific item we are looking for. A meaningful visualization technique may be the solution to this problem. We present VisMe, an interactive visualization tool that allows users to explore personal information. It integrates and uniformly displays relevant concepts in interconnected timelines. Each of these items (people, subjects and documents) can be progressively explored, creating new timelines, where several avenues can be simultaneously explored in context. VisMe allows relations between concepts to be explored in a straightforward way. By providing the means to interactively find relations between different kinds of information in order to retrieve personally relevant data, VisMe gives users insight into their digital selves that current tools have a hard time providing.
Duzentos leitões mestiços (Landrace × Large White) foram distribuídos em delineamento em blocos ao acaso, com quatro tratamentos e cinco repetições, com o objetivo de avaliar os efeitos de diferentes dietas sobre o desempenho e os pesos relativos e absolutos de fígado e pâncreas de leitões durante os períodos de aleitamento e pós-desmame, arraçoados dos 14 a 56 dias de idade. Os tratamentos consistiram de quatro dietas, as quais foram fornecidas aos animais dos 14 aos 42 dias de idade, quando então foram substituídas por uma dieta simples (ração de creche). Com base nos resultados, pode-se concluir que dietas contendo fontes de proteína de alta qualidade, como leite em pó integral e farinha de peixe, sem fonte suplementar de alimentos energéticos, como soro de leite, quando fornecidas a leitões dos 14 aos 42 dias de idade, proporcionaram os mesmos resultados de desempenho de leitões desmamados aos 28 dias de idade e recebendo rações simples à base de milho e farelo de soja.
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