PDT with methyl aminolevulinate is an excellent treatment option, particularly for patients with widespread damage or AK lesions in cosmetically sensitive areas.

No abstract

Cryosurgery is an effective treatment for actinic keratoses. The true complete response rate is significantly lower than that previously reported. The freeze duration influences successful treatment. Adverse events are mild and well tolerated.

A 59-year-old man presented with a psoriasiform dermatitis with associated bullae and destructive nail dystrophy of the hands and feet. He had lost 10 kg weight over 6 months and a mass in the neck was noted. He was provisionally diagnosed with Bazex syndrome (acrokeratosis paraneoplastica) and subsequent investigations revealed a squamous cell carcinoma in the right piriform fossa. His skin lesions were treated with oral psoralen and ultraviolet A phototherapy and this cleared the cutaneous changes, but the nail changes have persisted at 18 months follow up.

Three cases of unilateral pigmented purpuric eruption (UPPE) occurring in children aged between 7 and 12 years are reported. The lesions were asymptomatic and occurred on the lower limb and torso; one case demonstrated a quadrantic configuration with a sharp midline cutoff. The purpuric component resolved spontaneously within 3 months in all cases, while pigmentation showed partial resolution in the two cases followed up for 12 months. Our cases support previous reports of UPPE being a benign self-limiting condition mainly affecting young patients. The cause is unknown.