Elephantopus mollis and Elephantopus scaber were collected from Bay Nui region (An Giang province) for three years (2016)(2017)(2018)(2019). Their morphological characteristics, anatomical structures and medicinal powder were analyzed and compared with purpose of supplementing data to Elephantopus genus in Vietnam. The results showed that the morphological similarities of these two species occur at the sapling stage. At the mature stage, E. scaber has underground stem, purple flowers, and E. mollis has aerial stem, white flowers. In addition, these two species are able to be distinguished based on the size, thickness, tips shape or color of all leaves. The anatomical characteristics and the structure of the medicinal powder also showed differences in number and arrangement of xylem, and in covering trichomes of the two species at two stages (sapling and adult stages). Some byproducts such as calcium oxalate crystals, essential oil-secreting cells and inulin crystals were found in the vegetative organs of E. mollis and E. scaber collected from An Giang province.

Elephantopus mollis H.B.K. and Elephantopus scaber L. were collected atTo mountain in An Giang province and assessed for extraction efficiency, resistance ability to common bacterial strains in humans and animals, antioxidation, and toxicity. The extraction efficiency of two species was 11-26% and 16-28%, respectively and depending on the part of the plant. The flowers of both species had better antioxidant results than other parts with EC 50 at 32.2051 g/mL and 59.9778 g/mL, respectively, which was highly different from the rest of the plant (p<0.05). The leaves of both species had higher antibacterial properties than the other parts. For the six bacterial strains tested, both studied species had the strongest inhibiting ability for the growth of E. coli. (at a concentration of 200 mg/mL) different from that of Ampicillin (p<0.05). These two species were not toxic to Mus musculus at the dose of 8,000 mg/Kg.

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