Aim:The study was planned to evaluate the association of Impaired Glucose Tolerance and HbA1c with severity of acute pancreatitis. Material and methods: In present study Out of 133 patients diagnosed for Acute Pancreatitis; total 115 patients (n=115), of either gender of 18 to 65 years age groups were enrolled for the study. Patients with history of any acute or chronic illness like:-Diabetes Mellitus Impaired renal function, Hyperparathyroidism, Malnourished, Pregnant and lactating women and patients on calcium supplements were excluded. Result: The % of patients with impaired glucose tolerance was higher in patients suffering from severe pancreatitis. A signicant association was observed between impaired glucose tolerance and severity of pancreatitis (p ≤ 0.0001).Also signicant difference was observed in the HbA1c levels among three groups [mild, moderate and severe AP (p≤0.0001)]. Conclusion: The study concluded that a higher % of patients of severe pancreatitis group were diabetic or at risk of developing diabetes as compared to mild pancreatitis group.

Aim: The purpose of this study to evaluate the level of serum Albumin, Calcium and Albumin corrected calcium with severity of acute pancreatitis. Material and methods:The study was conducted in Department of Biochemistry in association with Department of Gastroenterology, Mahatma Gandhi Medical College & Hospital. In present study out of 133 patients diagnosed for Acute Pancreatitis; total 115 patients (n=115) of either gender of 18 to 65years age groups were enrolled for the study. Patients with history of any acute or chronic illness like: - Hyperparathyroidism, Diabetes Mellitus, Impaired renal function, Malnourished, Pregnant and lactating women and patients on calcium supplements were excluded. Result: Mean level of calcium decreased with progression in disease severity (p≤0.001).The mean Albumin Corrected Calcium was also signicantly lower in the patients presenting with severe and moderate acute pancreatitis compared with the mild acute pancreatitis patients (p≤0.0001). Conclusion: The study recommends hypocalcaemia and hypoalbuminemia as independent risk factors of progression towards severe pancreatitis. Similarly, albumin corrected calcium is suggested as a reliable marker for severity of pancreatitis.