In the present study, we have identified ten compounds, namely dodecanol acid, myristic acid, neophytadiene, palmitic acid, heptadecanoic acid, linoleic acid, elaidic acid, 3-7-dimethyl acid, stearic acid and methyl eicos acid, of the methanolic extract of Apamarga Kshara by GC-MS analysis. Apamarga Kshara has been reported to be active against cervical erosion. Major causal organism for cervical erosion is Trichomonas vaginalis. However, there is a paucity of information about the mechanism of action and inhibitory effect of the biologically active natural compounds presented in A. Kshara against this organism (T. vaginalis). Therefore, present investigation was conducted to observe possible interactions of these compounds on T. vaginalis carbamate kinase using molecular docking software 'AutoDock 4.2.' Identification of the amino acid residues crucial for the interaction between T. vaginalis carbamate kinase and these natural compounds is of due scientific interest. The study will aid in efficacious and safe clinical use of the above-mentioned compounds.
In order to determine how the average Indian's emissions may be reduced, one needs to understand the consumption basket and the implications of various categories of household consumption (such as cereals or durables) on emissions. With this in mind, this paper looks at consumption choices in India and calculates per capita carbon dioxide emissions of the different categories of consumption during 1987-1988 to 2007-2008. It is seen that both the increase in per person consumption and a change in the product basket have led to an increase in emissions per person. Further, the urban or higher class Indian emits more, not only because he consumes more of everything (compared, respectively, to the rural or lower class Indian), but also because of differences in the composition of consumption. Four products/product groups -fuel for cooking, fuel for lighting, durables and housing -are further explored to identify several problem products.
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