The complexes of ML 2 were synthesized where M= Co(II), Ni(II) and Cu(II) and L= 2-Butyl thioquinazoline 4 (3H)-semicarbazone (BTQS). The ligand have been synthesized by condensation of thioquinazoline-4(3H)-one with semicarbazide hydrochlande characterized by molar mass, elemental analysis, Infrared spectra, electronic spectra, magnetic susceptibility and molar conductance measurements. The ligand BTQS acts as neutral bidentate chelating agent and coordinated to metal ions through azomethine nitrogen and carbonyl oxygen of semicarbazone moiety. The remaining Coordination centres are satisfied by anions such as Cl

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INTRODUCTIONSchiff bases have the ability to act as coordinating ligands and the polynuclear complexes derived from Schiff bases find variety of applications in analytical and biological systems [1][2][3][4][5][6][7][8][9][10][11][12] . Schiff base complexes of transition metals are of great interest and have extensively been studied over past few decades [13][14][15][16] ABSTRACTIn the present paper, a series of complex of the type [MLX 2 ] where M = Co(II), Ni(II) and Cu(II), L = 6-methyl-2-phenyl-4H-chromen 4-thisemicarbazone (MPCT) have been synthesized. Their structure were confirmed by means of IR, electronic spectra, elemental analysis and molar conductance, coupled with magnetic susceptibility measurements. All the compounds were assayed for antibacterial activities against one gram positive bacterial strain Bacillus subtilis and one gram negative bacterial strain Eschericpia coli, using disc diffusion technique. It was observed on comparison with reference to antibiotic and fungicides. The complexes were found to be more effective than ligands. Schiff base coordination compounds, the present work was undertaken to study the complexes of Co(II), Ni(II) and Cu(II) ions with bioactive ligands. In the present paper, we report a series of new Co(II), Ni(II) and Cu(II) complexes of Schiff base 6-methyl-2-phenyl-4H-chromen-4-thiosemicarbazone. The complexes have general molecular formula [MLX 2 ]; where M = Co(II), Ni(II) and Cu(II); L = 6-methyl-2-phenyl-4H-chromen-4-thiosemicarbazone (MPCT) and X = Cl -, Br -, I -and NO 3 -.

Coordination compounds play a vital role in several fields Schiff base plays a central role in the field of coordination chemistry due to their biocidal activities including anticancer, antifungal, herbicidal and antibacterial. The high reactivity specificity and a number of Schiff bases in industry, medicine & agriculture are used in catalytic reaction and as biological models for understanding biomolecules. Schiff base compounds that are ABSTRACT A series of complexes having the formulae [M(MTQS) z X z ], where M = Co(II), Ni(II) and Cu(II), MTQS = 2-methyl thioquinazoline -4 (3H) semicarbazone, X = Cl -, Br -, I or NO 3 the ligand as well as metal complexes have been characterized by elemental analysis, magnetic susceptibility, molar conductance, electronic spectra and infrared spectra. On the basis of these studies the complexes of Co(II) and Ni(II) are reported to be octahedral geometry whereas Cu(II) complexes are imposed to be distorted octahedral in geometry. The complexes exhibit enhanced antifungal activity as compared to parent ligand.