Lymph nodes tuberculosis represents 30 percent of extra pulmonary tuberculosis in Morocco. We report here the experience of the pulmonology unit of the Avicenne Military Hospital in Marrakech for a period of 4 years. Our study interested 30 patients (15 males and 15 females) with an average age of 29 years old (10 to 62 years old). Tuberculosis has interested a single site in 28 patients, the other two patients had multiple but unilateral involvement. For the single sites, locations were jugulo-carotidian (20 patients), supra-calvicular (2 patients), axillary (2 patients), sub-mandibular (2 patients), spinal (2 patients) and mediastinal (2 patients). For the multiple locations, the involvement was jugulo-carotidian, sub-mandibular, spinal and sub-clavicular for one patient; and jugulo-carotidian and sub-clavicular for the other. Diagnosis was made by surgical biopsy and histology for all the patients. A six-month anti-tuberculous treatment was given afterward, with relapses in two patients.

La tuberculose représente un problème de santé publique dans le monde. Le traitement antibacillaire est un traitement prolongé associant plusieurs médicaments qui sont hépatotoxiques. La toxicité hépatique des antituberculeux est un effet secondaire sérieux qui peut limiter leur utilisation. L'identification des facteurs de risque en pratique permet d'individualiser une population à risque pour laquelle une surveillance rigoureuse doit être préconisée. Les hépatites cytolytiques sont les plus souvent en cause. Les antituberculeux responsables sont l'isoniazide (INH), la pyrazinamide (PZA), la rifampicine (RPM), et c'est leur association qui augmente le risque d'hépatotoxicité. La réin-troduction du traitement antituberculeux est possible après normalisation du bilan hépatique. Pour citer cette revue : J. Afr. Hépatol. Gastroentérol. 5 (2011). Mots clés Tuberculose · Traitement antituberculeux · Transaminases · HépatotoxicitéAbstract Tuberculosis represents a problem of public health worldwide. Antituberculosis treatment is longer and involves several drugs that can induce hepatotoxicity. Hepatotoxicity is a serious side effect that limits the use of antituberculosis drugs. Identification of the risk factors in practice allows us to identify patients for whom rigorous surveillance must be recommended. Cytolytic hepatitis is the most frequent clinical and biological aspect. The notable antituberculosis drugs responsible are isoniazid, pyrazinamid, and rifampicin, and their association increases the risk of hepatic toxicity. Reintroduction of the antituberculous treatment is possible after the normalization of the liver's function. To cite this journal: J. Afr. Hépatol. Gastroentérol. 5 (2011).

Leiomyoma is a benign smooth muscle tumor usually encountered in the uterus. Primary pulmonary localization is extremely rare in adults and children. However, it must be included in the differential diagnosis of any nodular lung lesion. Its treatment is surgical, with good long-term results. Here, we report a case of leiomyoma of lung parenchyma diagnosed in a 26-year-old man.

La localisation nasosinusienne de la tuberculose est rare. Elle est caractérisée par une présentation clinique polymorphe et non spécifique, posant souvent un problème de diagnostic différentiel. Le diagnostic repose sur l'examen anatomopathologique et bactériologique avec examen direct et culture. Le traitement est essentiellement médical à base d'antibacillaires.

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