The question of a healthy way of life of students in the conditions of quarantine restrictions is considered. The urgency of scientific research is caused by the sharp deterioration of the physical and mental condition of students due to the introduction of quarantine in the country caused by the COVID-19 pandemic, and in higher education institutions of distance learning. A necessary main prerequisite for maintaining health in quarantine is a healthy lifestyle, as a system of conditions that contribute to the strengthening and preservation of health. The purpose of the work is to identify areas for ensuring a healthy lifestyle of students during quarantine in the educational process of physical education. Research methods: theoretical analysis, systematization, comparison, generalization of literature data. According to the results of scientific research, the important and unique importance of physical education in the process of ensuring a healthy lifestyle of students has been proved. The directions of ensuring a healthy lifestyle of students during quarantine in the educational process of physical education are systematized: formation of students 'stable motivations for a healthy lifestyle application of all possible technologies in classroom and extracurricular physical education classes to educate students' needs and ability to maintain and improve their health. I; to provide students with a wide range of knowledge, on the basis of which the worldview of a healthy lifestyle should be formed; acquaintance of students with alternative methods of usual physical activity, for counteraction to negative consequences of quarantine and social isolation; development of programs and technological models of forming a healthy lifestyle by means of physical culture; development of methodical recommendations on physical education on the basis of innovative methods adapted for use at home during quarantine, in the situation of impossibility to use sports halls of educational institutions, sports clubs and playgrounds. The practical implementation of the findings is aimed at radical changes that will affect the development of physical education to ensure the health of students.