No abstract

Postpartum haemorrhage (PPH) is a fatal complication of the third stage of labour. PPH accounts for 25% maternal mortality worldwide. Fortunately most PPH cases are preventable and thus can significantly reduce maternal mortality and morbidity. Misoprostol, a PGE1 analogue, an uterotonic, is inexpensive, easily available with simple route of administration. The study group was given 600mcg of misoprostol within 5 min of clamping of cord and blood loss was measured with help of BRASS-V delivery drape. The parameters ascertained were total blood loss in third stage of labour, length of third stage, time taken for retraction of uterus, need of any additional uterotonic drug or surgical intervention, need for blood transfusion, adverse effect of 600mcg of oral misoprostol. Oral administration of 600mcg misoprostol is an effective method of preventing PPH, though it may not be as effective as potent uterotonics like ergometrine or PGF2alpha. Nevertheless, it scores over them in low resource settings due to its cost effectiveness, and ease of availability, transport, storage and administration to the patient.

BACKGROUND: The uterus remains quiescent throughout 9 months and begins to act on its own when full term is approached. Almost 50% women deliver in the duration of one week before and after the calculated EDD; and induction of labour is needed in about 20% of women: to increase the success of labour induction, to reduce the duration and complications of labour and to diminish the rate of caesarean sections. Cervical ripening is needed before induction of labour. There are many methods for induction of labour; however till date, none of them can claimed to be the best. To compare the AIM OF PRESENT STUDY: safety and efcacy of Dinoprostone gel versus intracervical foley's catheter for ripening of cervix and induction of labour. Compara MATERIAL AND METHODS: tive prospective study was conducted on 400 full term uncomplicated primigravida women needing induction of labour between January 2019 to June 2020 in department of obstetrics & gynecology at GMC Kota in Rajasthan.Group A: 200 women induced with Dinoprostone gel and Group B: 200 women induced with extra-amniotic Foley's catheter. Baseline characteristics like maternal age, gestational age, indication for induction were comparable in both the groups. The mean induction to delivery interval was shorter in RESULT: group A (12.69 ± 3.64 hours) as compared to Group B (18.17 ± 3.17 hours) and this difference was statistically highly signicant (P = 0.0001). There was no signicant difference observed in mode of delivery, labour progress at 18 hours, indication for caesarean section, maternal side effects, mean birth weight, Apgar score at 5 mins, number of NICU admissions between the two groups. The number of vaginal deliveries we CONCLUSION: re similar in both the groups but mean induction to delivery interval was signicantly shorter with Dinoprostone gel. However, the maternal and fetal outcomes were better in Foley's catheter group although the difference was not statistically signicant