Vinyl chloride has been associated recently with findings of angiosarcoma in animals and man. The present study examines the mortality experience of individuals occupationally exposed to vinyl chloride and lesser amounts of vinylidene chloride and other compounds. Employees were grouped into four exposure categories according to the highest levels of vinyl chloride exposure experienced for at least one month. Although no angiosarcomas were found and there were no deaths due to any liver malignancy, the observed malignancy deaths exceeded the expected among workers in the high-exposure category. Fewer than expected malignancy deaths were observed in the remaining exposure catergories.

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Two common over-the-counter medications may elevate urinary phenol to levels exceeding 75 mg/liter (ppm). This study presents data indicating that it is invalid to correct urinary phenol levels to specific gravity of 1.024. Animal studies indicate that having elevated urinary phenol levels secondary to phenyl salicylate ingestion are not harmful.

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Animal studies have indicated the carcinogenic potential of ethylene dibromide (EDB). Examination of the mortality experience of employees exposed to EDB in two Previous inhalation studies4 had indicated that rats exposed for up to six months to concentrations of 50 ppm EDB showed evidence of injury to the lungs, liver, kidney, and spleen. No tumours were observed in this series of six-month studies that included rabbits, monkeys, and guinea pigs, as well as rats. Studies were also conducted at 25 ppm. The authors concluded that "rabbits and monkeys and probably rats and guinea pigs can tolerate without adverse effects daily repeated seven-hour exposures to a vapour concentration of 25 ppm of ethylene dibromide."Bondi and Alumot5 found that one of two bull calves fed EDB at 10 mg/kg/day from the third day after birth showed signs of pneumonia, lack of co-ordination, and inability to stand at 5 weeks.