Purpose:The purpose is to study the correlation between dry eye and refractive errors in young adults using noninvasive Keratograph.Methods:In this cross sectional study, a total of 126 participants in the age range of 19–25 years and who were free of ocular surface disease, were recruited from King Saud University Campus. Refraction was defined by the spherical equivalent (SE) as the following: 49 emmetropic eyes (±0.50 SE), 48 myopic eyes (≤−0.75 SE and above), and 31 hyperopic eyes (>+0.75 SE). All participants underwent full ophthalmic examinations assessing their refractive status and dryness level including noninvasive breakup time (NIBUT) and tear meniscus height using Keratograph 4.Results:The prevalence of dry eye was 24.6%, 36.5%, and 17.4% in emmetropes, myopes, and hypermetropes, respectively. NIBUT has a negative correlation with hyperopia and a positive correlation with myopia with a significant reduction in the average NIBUT in myopes and hypermetropes in comparison to emmetropes.Conclusion:The current results succeeded to demonstrate a correlation between refractive errors and dryness level.

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The present study aims to evaluate the curative activity of freshwater crustacean extract (FCE) from freshwater crayfish Procambarus clarkii and silymarin on oxidative stress induced by carbon tetrachloride (CCl 4) in rat liver and erythrocytes. The degree of treatment in this activity has been measured by using biochemical parameters such as serum aspartate aminotransferase (ASAT), alanine aminotransferase (ALAT), alkaline phosphatase (ALP) and total protein as well as malondialdehyde (MDA), glutathione reduced (GSH), glutathione-S-transferase (GST) and catalase (CAT) in liver tissue and erytheocyte hemolysate. The FCE and silymarin produced significant antihepatotoxic effect by decreasing the activity of serum enzymes and MDA level, and increasing the serum total protein, GSH levels and the activities of GST and CAT in liver and erytheocyte hemolysate. From these results, it was suggested that FCE could ameliorate the liver and erythrocytes injuries perhaps, by its antioxidative effect, hence eliminating the deleterious effect of toxic metabolites from CCl 4 .