Recent studies have shown that the gut microbiota plays an important role in the pathogenesis of gastrointestinal diseases in various animal species. There are only limited data on the microbiome in cats with varying grades of dysbiosis. The purpose of the study was a detailed analysis of the quantitative and qualitative fecal microbiota spectrum in cats with intestinal dysbiosis of varying severity. The data obtained indicate that, depending on the dysbiosis severity in cats, the intestinal microbiome landscape changes significantly. It has been established that, depending on the dysbiosis severity, there is a shift in the balance between the Gram-positive and Gram-negative bacterial pools and in the nature of the isolation of specific bacteria forms, in the amount of obligate microbiota isolation, as well as individual facultative strains. When analyzing the serotyping of E. coli cultures isolated at various grades of intestinal dysbiosis severity, differences were found both in the isolation amount of various serotypes from one animal and in the prevalence of certain serotypes for each disease severity. A retrospective analysis of the fecal microbiota sensitivity in cats with dysbiosis to antibacterial drugs showed that, depending on the disease severity, the number of isolates sensitive to antibiotics increases significantly.

Chronic otitis externa of dogs is a significant problem due to the prevalence and complexity of the treatment of such animals. There is evidence that in 60–80% of cases of infectious diseases microorganisms located in the biofilm phenotype play the main role. Microorganisms in the biofilm phenotype have a number of advantages, the most significant of which is considered to be increased resistance to various external factors. Among them, a special place is occupied by resistance to antibiotics. In recent decades, research has been conducted at an increasing scale on the role of biofilm infections in various pathologies in veterinary medicine. The etiology and therapy of dog otitis externa caused by Malassezia pachydermatis biofilm has not been fully studied. This is why we consider relevant the scientific and practical aspects of research on the etiology and therapy of dog otitis externa from the position of biofilm infection. In this work, it has been statistically proven that there is a relationship between the optical density of Malassezia pachydermatis biofilms and their sensitivity to drugs, and this relationship is statistically significant. In addition, we have demonstrated that Farnesol has a good antibiofilm effect at a concentration of more 1.6 μM/mL (24% OD decrease of biofilm), and its highest antibiofilm effect (71–55%—more than a half) was observed at a concentration of 200–12.5 μM/mL.

The present study aims to investigate the effectiveness of bioformulations based on endophytic fungi to control apple scab and Valsa canker disease in two orchards in the Aurès region (Algeria). In both orchards, the results showed that the treatment of senescent apple leaves by invert emulsions containing Trichoderma longibrachiatum and Chaetomium globosum harmed the ascogenesis of winter forms of Venturia inaequalis by reducing the number of ascospore-ejecting asci, the number of morphologically mature asci, and a considerable increase in the immature asci number. This antifungal activity was more essential in soil-incorporated leaves, showing the importance of the combination of treatments with cultural practices to efficiently control the apple scab disease. Furthermore, the disease incidence decreased by 52.63% and 50.68% in R’haouat and Bouhmama orchards, respectively. Moreover, the treatment of Valsa ceratosperma cankers with a biogel containing the endophytic yeast Metschnikowia sp. led to wound healing varying from 43.52% and 87.97% after 120 days but remained more considerable than conventional treatment with Folicur (tebuconazol). The current results open real opportunities concerning the implementation of eco-friendly and potent apple protection systems.

On a worldwide basis increasing of meat production, especially beef, improving of its quality and reducing of costs are of great economic importance, and therefore intensification of livestock industry through introduction of advanced technologies, organization of full feeding, creation of optimal conditions for animals' welfare, breeding of the most productive breeds of young cattle are important. Young cattle of various productivity areas in Russia are grown to different weight conditions with different technologies of keeping and battening and their live weight and carcass weight are evaluated according to the interstate standard GOST 34120-2017 according to 7 categories. In 2018 production of livestock and poultry for slaughter (live weight) in farms of all categories in Russia amounted to 9 million tons and increased by 3.7 % compared to the same period in 2017. According to the Russian State Statistics of Federal Agency the volume of industrial meat production amounted to 1 690.6 thousand tons for the period from January till August in 2018 (11.2 % more than at the same period in 2017). Agricultural organizations produced 626.1 thousand tons of meat for the period from January till August in 2018 (almost 8 % more than at the same period in 2017). In 2018 according to the data from the Russian Ministry of Agriculture the average price of agricultural producers for cattle (live weight) was 109.57 thousand rubles per ton (w/o VAT), for half-carcass beef-209.25 thousand rubles per ton (w/o VAT), which are also higher compared to the data for 2017. Average consumer costs for beef-325.91 rubles per kg. In this work comparative assessment of average purchasing and consumer prices of live weight and carcasses of bulls and bullocks of various productivity areas was made, taking into account age of animals and technology of growing and battening by the category-super, prima, extra, excellent, good, satisfactory, low and evaluation of economic prospects for growing young stock to different weight conditions was given.

The emergence of new technologies, such as blockchain, Big Data, etc., provides fundamentally new opportunities for the formation of distributed databases necessary for assessing and managing hydrological risks in urbanized areas. At the same time, the use of the most modern technologies is based on adequate modeling and forecasting of hydrological processes, which, in the context of climatic changes and poorly predicted meteorological events for the long term, require close attention and understanding. The article deals with the tasks of risk assessment and prevention of damage from hazardous hydrological processes (rainfall floods, floods, mudflows, etc.) in framework of the Smart City Concept. Natural and anthropogenic factors of floods, methods of risk assessment and risk management in flooded areas are discussed. The issues of hazardous hydrological processes predictability and damage assessment are discussed. Sufficiency and effectiveness of the decisions made in the field of minimizing the negative impact of water, sufficiency of forces and means to ensure population safety and economic facilities are assessed on the example of the Kuban River basin.